Surgical · General

J9311

HCPCS drug code for the subcutaneous rituximab product combined with hyaluronidase, billed per 10 mg of rituximab, used for certain blood cancers.

3 sources ↓

Medicare
$0.00
Work RVU
0
Global, days
Region
General
Drawn from CMS

Documentation requirements

What must appear in the operative or office note to support the claim.

Source · Editorial brief grounded in 3 cited references ↓

  • Oncology diagnosis supporting the subcutaneous product
  • Rituximab mg given and units billed
  • Subcutaneous administration documented
  • NDC, lot, and discarded amount
  • Date of last dose in ortho pre-op notes

Applicable modifiers

Modifiers commonly billed with this code.

Source · AMA CPT modifier descriptors · CMS NCCI Policy Manual

What this code covers

Source · Editorial summary grounded in 3 cited references ↓

J9311 reports rituximab and hyaluronidase (Rituxan Hycela) per 10 mg. This is the subcutaneous oncology product for certain lymphomas and leukemias. It is not approved for rheumatoid arthritis, so rheumatology rituximab infusions are billed with J9312 or a biosimilar Q code instead.

An orthopedic practice will not bill J9311, but it matters in the chart. Lymphoma patients on rituximab show up with pathologic fractures, bone lesions, and joint complaints, and B-cell depletion raises infection risk for any procedure. Surgeons should know about recent doses before booking elective surgery.

If you are coding records for a multispecialty group, a few points: units are total rituximab mg divided by 10, the hyaluronidase is included in the code, and the admin is a subcutaneous injection, not an IV infusion. Single-dose vials need JW or JZ. Do not confuse this product with IV rituximab on the claim.

RVU & reimbursement

Component RVUs and Medicare national rate. Actual payment varies by GPCI locality.

Source · CMS Physician Fee Schedule, RVU26A · January 2026

Work RVU 0
Practice expense RVU 0
Malpractice RVU 0
Total RVU 0
Medicare national rate $0.00
Global period days

Payment by site of service

Medicare pays different rates by setting. HOPD typically pays substantially more than ASC for the same procedure.

Source · CMS OPPS Addendum B·ASC HCPCS payment rates·2026

SettingMedicare rate (national)
Office (PFS non-facility)
Procedure performed in physician's office
$0.00
HOPD (APC 9467)
Hospital outpatient department
$36.87

Common denial reasons

The recurring reasons claims for CPT J9311 get rejected.

Source · Editorial brief grounded in CMS NCCI edits, AAOS coding appeals, and cited references ↓

  • Billed for rheumatoid arthritis, which is not an approved use
  • IV rituximab billed under J9311
  • Units calculated on total volume instead of rituximab mg
  • Missing JW or JZ modifier
  • No prior authorization

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 3 cited references ↓

01What is the difference between J9311 and J9312?
J9311 is subcutaneous rituximab with hyaluronidase for certain blood cancers. J9312 is IV rituximab, used in both oncology and rheumatology.
02Can J9311 be used for rheumatoid arthritis?
No. The subcutaneous combination product is labeled for oncology only.
03Why should an orthopedic surgeon know about rituximab?
Rituximab depletes B cells and raises infection risk, which affects timing of elective procedures.

Sources & references

Editorial content was developed using the following public sources.

  1. 01CMS Physician Fee Schedule 2026
  2. 02CMS Medicare Part B Drug Average Sales Price files
  3. 03
    cms.gov
    https://www.cms.gov/medicare/payment/fee-schedules/physician

Mira Scribe

Mira Scribe notes capture active cancer treatment and recent rituximab doses at the ortho visit, so infection risk is visible before a procedure is planned.

See how Mira captures CPT J9311 documentation

Related CPT codes

Ready to transform your orthopedic practice?

See how orthopedic practices are running documentation, billing, and operations on a single voice-first platform.

Request Access