ICD-10-CM · Spine

M45.7

Ankylosing spondylitis localized to the lumbosacral region of the spine, capturing inflammatory involvement at the junction of the lumbar vertebrae and sacrum.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
12
Region
Spine
Drawn from CDCICD10DataAAPCAsahqCdek

Documentation tips

What should appear in the chart to support M45.7.

Source · Editorial brief grounded in 5 cited references ↓

  • Explicitly name the lumbosacral region in the clinical note — 'lumbar' or 'sacral' alone maps to a different M45 subcategory.
  • Document HLA-B27 test result and date, as this supports inflammatory versus degenerative diagnosis distinction.
  • Record radiographic or MRI findings: sacroiliitis grade, syndesmophytes, or erosions at the lumbosacral junction.
  • Note the duration and pattern of back pain (morning stiffness, nocturnal pain, improvement with activity) to establish inflammatory back pain criteria.
  • If multiple spinal regions are involved, document each region explicitly so the coder can determine whether M45.0 or M45.7 applies.
  • Record elevated inflammatory markers (CRP, ESR) in the same encounter note to support active inflammatory disease coding.

Related CPT procedures

Procedure codes commonly billed with M45.7. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

72100 $40.42
Radiologic examination of the lumbosacral spine capturing two or three views, used to evaluate the lumbar vertebrae and sacrum for injury, degeneration, or structural abnormality.
72110 $53.44
Radiologic examination of the lumbar spine (lumbosacral) with a minimum of four views, including oblique and/or bending views.
72114 $61.79
Radiologic examination of the lumbosacral spine, complete series with bending (flexion/extension) views — minimum of 6 views total.
72148 $191.72
Non-contrast MRI of the lumbar spine used to evaluate disc pathology, spinal stenosis, nerve root compression, and other structural abnormalities without administration of contrast material.
72158 $318.31
MRI of the lumbar spinal canal and its contents performed first without contrast, then repeated after contrast administration for enhanced visualization.
99213 $95.19
Established patient office or outpatient visit requiring 20–29 minutes of total time or low-complexity medical decision-making.
99214 $135.61
Office visit for an established patient requiring moderate-complexity medical decision making (MDM), or 30–39 minutes of total provider time on the date of service.
99215 $192.39
Highest-level office or outpatient E/M visit for an established patient, qualifying via high-complexity medical decision making or 40–54 minutes of total provider time on the date of service.
20610 $68.81
Aspiration and/or injection of a major joint or bursa (shoulder, hip, knee, or subacromial bursa) performed without ultrasound guidance.
77080 View procedure details
72295 View procedure details
77085 View procedure details

Common coding pitfalls

The recurring mistakes coders make with M45.7 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Reporting M45 (non-billable parent) instead of M45.7 — the parent code will be rejected; always code to the 4th-character level.
  • Confusing M45.6 (lumbar region) with M45.7 (lumbosacral region) — the lumbosacral code applies only when the provider documents involvement at the L5-sacrum junction, not the lumbar spine broadly.
  • Using M45.7 when the diagnosis is juvenile ankylosing spondylitis — that maps to M08.1, which is an Excludes1 exclusion at the M45 category level.
  • Applying M45.7 when Reiter's disease (reactive arthritis) is the underlying cause of spinal arthropathy — use M02.3- instead.
  • Defaulting to M45.9 (unspecified site) when the note documents lumbosacral involvement — M45.9 is a valid code but signals incomplete documentation and may not satisfy LCD specificity requirements.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M45.7 is the correct billable code when the provider documents ankylosing spondylitis (AS) with involvement specifically at the lumbosacral region — the transitional zone between L5 and the sacrum. This is distinct from M45.6 (lumbar region only) and M45.8 (sacral and sacrococcygeal region). If the documented involvement spans multiple spinal regions, use M45.0 instead. Never report the parent code M45 alone — it is non-billable and will trigger a claim rejection.

The lumbosacral region is a common site of early AS involvement given its proximity to the sacroiliac joints. Supporting documentation typically includes radiographic sacroiliitis, HLA-B27 status, inflammatory back pain history (onset before age 45, worse with rest, improved with movement), and elevated CRP or ESR. These findings anchor the diagnosis and satisfy LCD/NCD criteria when applicable.

For AS, the Excludes1 notes at the M45 category level are critical: do not use M45.7 when the underlying condition is arthropathy in Reiter's disease (M02.3-) or juvenile ankylosing spondylitis (M08.1). Behçet's disease (M35.2) is listed as Excludes2, meaning it can be coded separately if both conditions are independently documented.

Sibling codes

Other billable codes under M45 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01What is the difference between M45.6 and M45.7?
M45.6 covers ankylosing spondylitis of the lumbar region; M45.7 is specific to the lumbosacral region (the L5-sacrum junction). Use whichever matches the provider's documented anatomic location precisely.
02Can I use M45.7 if the note says ankylosing spondylitis without specifying the region?
No. Without documented regional specificity, use M45.9 (unspecified sites in spine). Query the provider to confirm lumbosacral involvement before assigning M45.7.
03Is M45.7 appropriate for juvenile ankylosing spondylitis in the lumbosacral region?
No. Juvenile ankylosing spondylitis is an Excludes1 condition under M45 — use M08.1 regardless of the spinal region involved.
04Does M45.7 require a 7th-character extension?
No. M45.7 is an M-code (musculoskeletal disease category) and does not use 7th-character extensions. Those apply to S-code injury categories.
05What if the patient has AS affecting both the lumbosacral region and the thoracic spine?
When AS involves multiple spinal regions in the same patient, use M45.0 (multiple sites in spine) rather than coding each region separately.
06Can M45.7 be coded alongside a sacroiliac joint injection CPT code?
Yes. M45.7 can support medical necessity for sacroiliac joint procedures when the note documents active lumbosacral AS with SI joint involvement — verify individual payer LCD criteria.
07Does Behçet's disease exclude the use of M45.7?
No, Behçet's disease (M35.2) is listed as Excludes2 under M45, meaning both codes can be reported together if both conditions are independently documented and clinically present.

Mira AI Scribe

Mira's AI scribe captures the provider's documented spinal region (lumbosacral), inflammatory back pain characteristics, HLA-B27 result, and imaging findings (sacroiliitis grade, syndesmophytes) at the point of encounter. This prevents downcoding to the unspecified M45.9, blocks rejection from the non-billable M45 parent, and ensures the record supports LCD/NCD criteria for biologic therapy authorizations tied to confirmed AS diagnosis.

See how Mira captures M45.7 documentation

Related ICD-10 codes

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