ICD-10-CM · Spine

M49.83

M49.83 identifies a spondylopathy of the cervicothoracic region (C7–T1 junction) that arises as a manifestation of an underlying disease classified elsewhere — not as a primary spinal diagnosis.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
12
Region
Spine
Drawn from CDCICD10DataAAPCFindacodeCMS

Documentation tips

What should appear in the chart to support M49.83.

Source · Editorial brief grounded in 5 cited references ↓

  • Identify and document the underlying systemic or infectious disease driving the spondylopathy — M49.83 cannot stand alone; the primary condition must appear first in the claim's diagnosis sequence.
  • Specify the cervicothoracic region explicitly (C7–T1 junction) in the clinical note; vague 'cervical spine' documentation may push the coder to M49.82 or M49.80 instead.
  • Record imaging findings that confirm spinal structural involvement at the cervicothoracic level — curvature changes, deformity, kyphosis, or scoliosis — since M49 includes all of these manifestations.
  • If multiple spinal levels are involved, document each level clearly so the coder can determine whether M49.83 alone covers the region or whether M49.89 (multiple sites) is more accurate.
  • Note whether the spondylopathy is neuropathic in character; neuropathic variants driven by syringomyelia (G95.0) or tabes dorsalis (A52.11) are Excludes1 and cannot be coded with M49.83.

Related CPT procedures

Procedure codes commonly billed with M49.83. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

22551 $1,604.91
Anterior cervical discectomy and fusion (ACDF) at a single interspace, performed through a front-of-neck approach with removal of disc material and arthrodesis of adjacent vertebral bodies.
22552 $353.05
Add-on code for each additional cervical interspace fused via anterior interbody approach during the same session as the primary procedure (22551), including disc space preparation, discectomy, osteophytectomy, and spinal cord or nerve root decompression below C2.
22554 $1,215.79
Anterior interbody arthrodesis of the cervical spine below C2, performed via anterior approach with minimal diskectomy to prepare the interspace for fusion — not performed for decompression purposes.
22600 $1,282.93
Posterior or posterolateral cervical spinal fusion at a single interspace below C2, performed through a posterior approach to achieve bony arthrodesis.
22612 $1,467.64
Posterior or posterolateral lumbar arthrodesis of a single interspace, performed via a posterior approach with bone graft and typically pedicle screw fixation to achieve vertebral segment fusion.
72040 $39.75
Radiologic examination of the cervical spine capturing two or three views (e.g., AP, lateral, oblique).
72050 $55.11
Radiologic examination of the cervical spine capturing a minimum of four views, used to evaluate alignment, fractures, degeneration, or other structural pathology of the neck.
72052 $62.79
Radiologic examination of the cervical spine using six or more distinct views, the highest-level plain-film cervical series in the CPT spine imaging family.
72070 $33.07
Two-view radiologic examination of the thoracic spine, including AP and lateral projections of the 12 thoracic vertebrae.
99213 $95.19
Established patient office or outpatient visit requiring 20–29 minutes of total time or low-complexity medical decision-making.
99214 $135.61
Office visit for an established patient requiring moderate-complexity medical decision making (MDM), or 30–39 minutes of total provider time on the date of service.
99215 $192.39
Highest-level office or outpatient E/M visit for an established patient, qualifying via high-complexity medical decision making or 40–54 minutes of total provider time on the date of service.

Common coding pitfalls

The recurring mistakes coders make with M49.83 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Sequencing M49.83 first instead of the underlying disease — the Tabular List instructs 'code first underlying disease'; reversing this order violates ICD-10-CM sequencing rules and can trigger a claim edit.
  • Using M49.83 when the underlying condition has its own specific spinal code with an Excludes1 note (e.g., coding M49.83 alongside A18.01 for tuberculous spondylitis — that combination is explicitly prohibited).
  • Defaulting to M49.82 (cervical region) when pathology is documented at C7–T1; the cervicothoracic region is a distinct classification and M49.83 is the correct code for that junction.
  • Assigning M49.83 for primary degenerative disc disease or idiopathic spondylosis — M49.8x codes require an underlying disease classified elsewhere; standalone degenerative conditions belong in M47.- or M50.-.
  • Failing to check whether the systemic disease driving the spondylopathy is one of the Excludes1-listed conditions before submitting M49.83, which will result in a coding conflict on audit.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M49.83 is a manifestation code, meaning the cervicothoracic spondylopathy it describes is secondary to a systemic or infectious disease. The underlying condition must be coded first, per the ICD-10-CM 'code first' instruction at the M49 category level. Underlying diseases that drive M49.83 include brucellosis (A23.-), Charcot-Marie-Tooth disease (G60.0), enterobacterial infections (A01–A04), and osteitis fibrosa cystica (E21.0), among others. The M49.83 code then follows in the diagnosis sequence to capture the spinal manifestation at the cervicothoracic region.

The cervicothoracic region in ICD-10-CM refers to the C7–T1 articulation. If pathology spans into the pure cervical region (C1–C6), use M49.82 instead; for the upper thoracic region alone, use M49.84. If documentation supports involvement at multiple non-contiguous spinal regions, M49.89 (multiple sites) may be appropriate — though that ambiguity should be resolved with the treating provider before coding.

M49.83 carries a hard Excludes1 fence that blocks several codes from being assigned simultaneously: tuberculous spondylitis (A18.01), syphilitic spondylitis (A52.77), neuropathic spondylopathy in tabes dorsalis (A52.11), neuropathic spondylopathy in syringomyelia (G95.0), nonsyphilitic neuropathic spondylopathy NEC (G98.0), gonococcal spondylitis (A54.41), typhoid fever spondylitis (A01.05), and enteropathic arthropathies (M07.-). If the underlying disease is one of those, use the disease-specific code rather than M49.83.

Sibling codes

Other billable codes under M49.8 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01Does M49.83 get listed first on the claim?
No. M49.83 is a manifestation code. The underlying disease (e.g., brucellosis A23.-, Charcot-Marie-Tooth G60.0) must be sequenced first; M49.83 follows to identify the cervicothoracic spinal manifestation.
02What anatomical region does M49.83 cover?
The cervicothoracic region corresponds to the C7–T1 junction. Pathology limited to C1–C6 maps to M49.82; pathology at the thoracic region alone maps to M49.84.
03Can M49.83 be used for tuberculous spondylitis at the cervicothoracic level?
No. Tuberculous spondylitis is coded with A18.01, which appears on the Excludes1 list for M49. These two codes cannot be assigned together; A18.01 fully captures the spinal involvement.
04Is M49.83 appropriate when a patient has degenerative disc disease at C7–T1 with no systemic underlying condition?
No. M49.83 requires an underlying disease classified elsewhere. Idiopathic or degenerative disc pathology at C7–T1 belongs under M50.- (cervical disc disorders) or M47.- (spondylosis), not M49.-.
05What is the difference between M49.83 and M46.83?
M46.83 is other specified inflammatory spondylopathy at the cervicothoracic region — used for inflammatory conditions without a separately classified underlying disease. M49.83 specifically requires a documented underlying systemic or infectious disease driving the spinal manifestation.
06Can M49.83 and M49.82 be coded together if both the cervical and cervicothoracic regions are involved?
If pathology is documented at multiple non-contiguous spinal sites, consider M49.89 (multiple sites in spine) after confirming with the provider. Stacking adjacent region codes without explicit documentation of distinct involvement at each level is an audit risk.
07Which CPT procedures most commonly pair with M49.83?
Cervicothoracic fusion procedures (22551, 22552, 22600), spinal imaging (72050, 72052, 72070), and evaluation and management visits (99213–99215) are typical pairings, depending on the clinical scenario and the underlying disease being managed.

Mira Scribe

Mira's AI scribe captures the treating provider's documented link between the systemic or infectious diagnosis and the cervicothoracic spinal manifestation — including the specific region (C7–T1), any curvature, deformity, or structural changes on imaging, and the sequenced primary condition. That documentation chain prevents sequencing errors, blocks Excludes1 conflicts, and stops M49.83 from landing on a claim without its required underlying disease code.

See how Mira captures M49.83 documentation

Related ICD-10 codes

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