ICD-10-CM · General

M72.4

M72.4 classifies pseudosarcomatous fibromatosis, a rapidly growing but benign soft-tissue lesion of fibroblastic origin — also captured under this code when the operative or pathology report uses the term nodular fasciitis.

Verified May 8, 2026 · 4 sources ↓

Status
Billable
Chapter
13
Related CPT
7
Region
General
Drawn from CDCICD10DataAAPCIcd

Documentation tips

What should appear in the chart to support M72.4.

Source · Editorial brief grounded in 4 cited references ↓

  • Record the anatomic site of the lesion (e.g., forearm, thigh, chest wall) in the note — M72.4 has no laterality digits, but site specificity supports medical necessity and distinguishes the claim from unspecified soft-tissue disorder codes.
  • Obtain and reference the pathology report explicitly in the assessment; pseudosarcomatous fibromatosis/nodular fasciitis is a histologic diagnosis and payer audits will look for pathologic confirmation.
  • Document clinical features that differentiated this lesion from a malignant soft-tissue neoplasm (rapid growth, superficial location, patient age, imaging characteristics) to substantiate the benign fibroblastic diagnosis and justify any prior workup billed alongside.
  • If the mass was previously coded with an unspecified soft-tissue mass or neoplasm code pending biopsy, update the diagnosis to M72.4 once pathology confirms — retroactive code correction may be needed on the surgical claim.
  • Note any prior conservative management or imaging (MRI, ultrasound) in the record to support the decision tree leading to excision or biopsy.

Related CPT procedures

Procedure codes commonly billed with M72.4. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M72.4 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Assigning M72.4 based on clinical suspicion alone, before pathology results are available — this code requires a confirmed histologic diagnosis of pseudosarcomatous fibromatosis or nodular fasciitis.
  • Confusing M72.4 with neoplasm codes: nodular fasciitis is benign, but its rapid growth can prompt providers to document 'rule out sarcoma,' leading coders to mistakenly use a neoplasm code (D21.x or C49.x range) before pathology is finalized.
  • Routing retroperitoneal fibromatosis to M72.4 — the M72 category carries an Excludes2 for retroperitoneal fibromatosis, which belongs at D48.3.
  • Failing to update the diagnosis code from a provisional soft-tissue mass code to M72.4 after pathology confirms nodular fasciitis, leaving the surgical claim coded to a less specific or incorrect diagnosis.

Clinical context

Source · Editorial summary grounded in 4 cited references ↓

M72.4 covers pseudosarcomatous fibromatosis and its ICD-10-CM synonym, nodular fasciitis. Nodular fasciitis is a non-encapsulated benign proliferation of fibroblasts arising from soft tissue, characterized histologically by spindle-shaped fibroblasts, osteoclast-like giant cells, chronic inflammatory infiltrate, red blood cell extravasation, and high mitotic activity in a storiform pattern. The lesion grows rapidly, which frequently triggers a clinical or imaging concern for sarcoma — hence the 'pseudosarcomatous' designation. Pathology confirmation is typically required before this code is applied.

In orthopedic practice, M72.4 appears most often after excision or biopsy of a soft-tissue mass whose pathology returns nodular fasciitis. Use it at the postoperative or post-biopsy visit once the diagnosis is confirmed. Do not use M72.4 when the provider documents only a 'soft-tissue mass' or 'fibromatosis' without pathologic specificity — those scenarios map elsewhere within M72 or to neoplasm codes depending on clinical context.

Note the Excludes2 at the M72 category level: retroperitoneal fibromatosis is separately coded to D48.3 and must not be captured here. M72.4 has no laterality substructure; the code is the same regardless of which extremity or body region is affected.

Inclusion & exclusion notes

Per the official ICD-10-CM Tabular List.

Source · CDC ICD-10-CM Official Tabular List · 2026

Includes

  • Nodular fasciitis

Sibling codes

Other billable codes under M72 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 4 cited references ↓

01Is nodular fasciitis the same code as pseudosarcomatous fibromatosis?
Yes. The ICD-10-CM Tabular List lists 'Nodular fasciitis' as an Applicable To term under M72.4, making it a direct synonym for coding purposes. Use M72.4 for either term when pathology confirms the diagnosis.
02Does M72.4 have laterality or 7th-character extensions?
No. M72.4 is a complete 4-character billable code with no laterality substructure and no 7th-character requirement. Document the affected side in the clinical note for record completeness, but the code itself does not vary by side.
03Can I assign M72.4 before biopsy or pathology results are back?
No. Pseudosarcomatous fibromatosis is a histologic diagnosis. Before pathology confirms it, code the presenting sign (e.g., soft-tissue mass, M79.89x) rather than M72.4. Update to M72.4 once the pathology report supports it.
04What DRGs does M72.4 group to?
Per MS-DRG v43.0, M72.4 groups to DRG 557 (Tendonitis, myositis and bursitis with MCC) or DRG 558 (Tendonitis, myositis and bursitis without MCC), depending on the presence of a major complication or comorbidity.
05Should I use M72.4 or a neoplasm code if the lesion was initially suspected to be a sarcoma?
Use the confirmed diagnosis. Once pathology returns nodular fasciitis, assign M72.4. Do not use a malignant neoplasm code (C49.x) for a lesion confirmed as benign. If pathology is still pending at the time of claim submission, use the appropriate unspecified soft-tissue mass code and amend after results are received.
06Is retroperitoneal fibromatosis coded to M72.4?
No. The M72 category carries an Excludes2 note directing retroperitoneal fibromatosis to D48.3. M72.4 is for soft-tissue fibroblastic lesions outside that anatomic site.
07What CPT procedures most commonly pair with M72.4?
Soft-tissue excision codes (e.g., 27327, 27328 for thigh/knee region; 25075, 25076 for forearm/wrist; 21931, 21932 for trunk) and surgical pathology code 88305 for histologic examination are the most frequent pairings, depending on anatomic site.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (effective October 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M70-M79/M72-/M72.4
  3. 03
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M72.4
  4. 04
    icd.who.int
    https://icd.who.int/browse10/2019/en#M72.6

Mira AI Scribe

The Mira AI Scribe captures the anatomic location of the soft-tissue lesion, clinical characteristics (rapid growth, size, depth relative to fascia), relevant imaging findings, and — critically — the pathology report language confirming nodular fasciitis or pseudosarcomatous fibromatosis. Having this detail in the encounter note prevents downcoding to an unspecified fibroblastic disorder and preempts payer requests for records to substantiate the benign-versus-malignant distinction.

See how Mira captures M72.4 documentation

Related ICD-10 codes

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