ICD-10-CM · Multi-region

M65.19

Infective tenosynovitis or synovitis caused by a pathogen (bacterial, mycobacterial, or other organism) affecting multiple anatomical sites simultaneously, not classifiable to a single-region subcode under M65.1.

Verified May 8, 2026 · 4 sources ↓

Status
Billable
Chapter
13
Related CPT
8
Region
Multi-region
Drawn from CDCICD10DataAAPC

Documentation tips

What should appear in the chart to support M65.19.

Source · Editorial brief grounded in 4 cited references ↓

  • Name every affected site explicitly (e.g., 'right wrist and left ankle tenosynovitis') — 'multiple joints' without enumeration leaves the coder without confirmation that M65.19 is correct over a single-site code.
  • Document the suspected or confirmed causative organism; pair M65.19 with an organism code (e.g., B96.89, A54.49) per ICD-10-CM etiology/manifestation convention.
  • Record any imaging findings — ultrasound or MRI evidence of tendon sheath effusion or synovial thickening — to support medical necessity for joint aspiration or advanced imaging CPT codes.
  • Specify acuity and clinical course (acute vs. subacute vs. chronic) to distinguish infectious from degenerative or use-related tenosynovitis and to prevent Excludes1 conflicts with M70.- codes.
  • If culture or sensitivity results are pending at time of coding, document 'suspected infectious tenosynovitis' and the clinical basis — the coder can assign M65.19 based on provider documentation of infective etiology, consistent with outpatient confirmed-diagnosis guidelines.

Related CPT procedures

Procedure codes commonly billed with M65.19. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M65.19 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Defaulting to M65.19 when the chart documents only one site — a single-site presentation belongs at M65.11–M65.18, not the 'multiple sites' code.
  • Using M65.19 for overuse-related tenosynovitis (e.g., de Quervain's) when no infectious cause is documented — those cases belong under M65.4 or M70.- categories, not M65.1x.
  • Omitting the organism code: M65.19 captures the anatomical manifestation; the causative pathogen requires an additional code from A00–B99 or B95–B98 per ICD-10-CM instructional notes.
  • Confusing M65.19 (infective, multiple sites) with M65.10 (infective, unspecified site) — use M65.10 only when site is genuinely undocumented, not when multiple sites are documented.
  • Applying M65.19 to post-traumatic tendon sheath inflammation — current injuries trigger Excludes1 and must be coded with the appropriate S-code injury category instead.

Clinical context

Source · Editorial summary grounded in 4 cited references ↓

M65.19 is the correct code when a provider documents infectious synovitis or tenosynovitis that spans multiple joint or tendon sheath sites and does not fit a single anatomical location under the M65.1x subcategory. Common clinical scenarios include disseminated gonococcal tenosynovitis involving the wrists and ankles together, or septic tenosynovitis in an immunocompromised patient presenting at several tendon sheaths simultaneously. The causative organism should be coded additionally using a B95–B98 or A-chapter code per ICD-10-CM conventions.

M65.19 sits under parent M65.1 (Other infective (teno)synovitis) and is distinct from M65.10 (unspecified site) and the single-site subcodes (M65.11–M65.18). Do not use M65.19 simply because site documentation is incomplete — if the documentation names a single site, use the appropriate site-specific code. The 'multiple sites' designation requires clinical documentation confirming more than one discrete anatomical region is infected.

Note the Excludes1 rules attached to M65: do not assign M65.19 for current tendon or ligament injuries (code by body-region injury category), chronic crepitant synovitis of hand and wrist (M70.0-), or soft tissue disorders related to use, overuse, and pressure (M70.-). These are hard exclusions, not optional cross-references.

Sibling codes

Other billable codes under M65.1 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 4 cited references ↓

01When does M65.19 apply instead of a single-site M65.1x code?
Use M65.19 only when the provider documents infectious tenosynovitis or synovitis at more than one discrete anatomical region in the same encounter. If only one site is affected, use the corresponding site-specific subcode (M65.11–M65.18).
02Do I need a separate organism code with M65.19?
Yes. ICD-10-CM instructs coders to assign an additional code from B95–B98 to identify the bacterial agent, or the appropriate A-chapter code for specific organisms such as gonococci (A54.49) or mycobacteria. M65.19 alone is incomplete when organism identity is documented.
03Can M65.19 be used for reactive or post-traumatic synovitis affecting multiple joints?
No. M65.19 is limited to infective (pathogen-driven) tenosynovitis. Reactive arthropathy belongs under M02.- and current traumatic tendon involvement triggers the Excludes1 rule, requiring an S-code injury category instead.
04What Excludes1 conditions must I rule out before assigning M65.19?
Per the M65 category notes: chronic crepitant synovitis of hand and wrist (M70.0-), current tendon or ligament injuries coded by body region, and soft tissue disorders related to use, overuse, or pressure (M70.-) are all Excludes1 — they cannot be coded at the same encounter as M65.19 if they explain the same condition.
05Is M65.19 valid for outpatient and inpatient claims equally?
Yes, M65.19 is a fully billable code in both settings. For outpatient claims, assign it only when the provider has documented an infective etiology — do not assign based on 'suspected' or 'probable' infectious cause per outpatient coding guidelines.
06How does M65.19 differ from M65.10?
M65.10 is used when the site of infective tenosynovitis is unspecified or not documented. M65.19 requires explicit documentation of involvement at multiple anatomical sites. If site documentation is genuinely absent, M65.10 is correct; if multiple sites are named, M65.19 applies.
07What physical therapy or imaging CPT codes commonly accompany M65.19?
Joint aspiration codes (20600, 20605, 20610 depending on joint size), ultrasound guidance (77002), and MRI of the affected regions (73218 for upper extremity, 73221 for joint) are commonly billed alongside M65.19 for diagnostic and procedural workup of multi-site infectious tenosynovitis.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 — M65.19
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M65-M67/M65-/M65.19
  3. 03
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M65.19
  4. 04
    cdc.gov
    https://www.cdc.gov/nchs/icd/icd-10-cm/index.html

Mira AI Scribe

The Mira AI Scribe captures the provider's documentation of each affected tendon sheath or synovial site by name, the clinical or laboratory basis for an infectious etiology, any organism identified on culture or Gram stain, and the treatment plan (aspiration, antibiotics, imaging ordered). Capturing all affected sites by name prevents a downcode to M65.10 (unspecified site) and ensures the organism code is populated — both of which are audit triggers under M65.1x claim review.

See how Mira captures M65.19 documentation

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