ICD-10-CM · Spine

M46.58

M46.58 identifies infectious disease involving the vertebral structures of the sacral and sacrococcygeal region — the lower sacrum through the coccyx — caused by pathogens other than those classified under pyogenic or tuberculous spondylitis codes.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
11
Region
Spine
Drawn from CDCICD10DataAAPCCMSMS

Documentation tips

What should appear in the chart to support M46.58.

Source · Editorial brief grounded in 5 cited references ↓

  • Specify anatomical level explicitly: 'sacral,' 'sacrococcygeal,' or 'coccyx' — generic 'low back' won't support M46.58 over a lumbar or lumbosacral code.
  • Record the causative organism or pathogen class (bacterial, fungal, brucellar) and reference positive culture, serology, or biopsy results to substantiate the infectious etiology.
  • Document imaging findings — MRI signal changes at the sacrum, CT-guided biopsy results, or bone scan uptake — that confirm an infective rather than inflammatory or neoplastic process.
  • If conservative treatment with antibiotics preceded surgical intervention, document that failure of non-operative management in the note to support medical necessity for any procedural coding.
  • Note any systemic infectious findings (fever, elevated ESR/CRP, positive blood cultures) that corroborate the infectious spondylopathy diagnosis.

Related CPT procedures

Procedure codes commonly billed with M46.58. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M46.58 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Defaulting to M46.57 (lumbosacral) when the documented site is clearly the sacrum or sacrococcygeal region — the two are distinct anatomical locations with different codes.
  • Using M46.58 for sacroiliac joint infections; septic sacroiliitis maps instead to M01.x5x (direct infection of hip/pelvic joints) or relevant infectious arthritis codes, not the spondylopathy block.
  • Assigning M46.58 when the infection is pyogenic vertebral osteomyelitis — that presentation belongs in M46.2x, not M46.5x.
  • Failing to code also the causative organism (e.g., B01–B99 range) when known — the Tabular List Use Additional Code instruction applies to the M46.5x category.
  • Selecting M46.50 (site unspecified) when the provider has documented the sacral level — unspecified codes trigger payer scrutiny and reduce DRG accuracy.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M46.58 applies when a confirmed or suspected infectious process affects the sacral or sacrococcygeal spine and the causative organism or clinical picture does not fit pyogenic vertebral osteomyelitis (M46.2x), discitis (M46.3x–M46.4x), or tuberculous spondylitis (A18.01). Typical scenarios include sacral involvement from brucellosis, fungal organisms, or other atypical pathogens, as well as infectious sacrococcygeal pathology where the organism is known but doesn't map to a more specific code elsewhere in Chapter 13.

The sacral and sacrococcygeal designation makes M46.58 one of the most anatomically specific codes in the M46.5x family. Sibling codes cover the occipitoatlantoaxial region (M46.51), cervical (M46.52), cervicothoracic (M46.53), thoracic (M46.54), thoracolumbar (M46.55), lumbar (M46.56), lumbosacral (M46.57), and multiple sites (M46.59). If infection spans both lumbosacral and sacral levels, M46.59 (multiple sites) is the better fit.

From a DRG perspective, M46.58 groups into MS-DRG 456–458 when paired with a spinal fusion procedure, and into MS-DRG 551–552 (medical back problems) in non-operative management. Accurate code assignment directly affects DRG weight, so distinguishing M46.58 from lumbosacral (M46.57) or unspecified (M46.50) is not trivial.

Sibling codes

Other billable codes under M46.5 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01What distinguishes M46.58 from M46.57 (lumbosacral region)?
M46.57 covers the lumbosacral junction (L5–S1 level), while M46.58 applies to the sacrum proper and the sacrococcygeal segment. If imaging and documentation clearly place infection at or below the sacral base rather than at the L5–S1 disc space, M46.58 is correct.
02Should I code the organism separately when using M46.58?
Yes. The M46.5x category carries a 'Use Additional Code' instruction to identify the infectious agent. Add the appropriate organism code from B95–B97 (bacteria/viruses) or B35–B49 (fungi), or a specific infectious disease code when applicable (e.g., A23.x for brucellosis).
03Can M46.58 be used for a sacral pilonidal cyst infection?
No. Pilonidal cyst with abscess maps to L05.01 or L05.02, not to the infective spondylopathy block. M46.58 requires involvement of the sacral or sacrococcygeal vertebral structures — disc, endplate, or bone — not overlying soft tissue.
04When should I use M46.59 (multiple sites) instead of M46.58?
Use M46.59 when the infectious process spans the sacral region and at least one other named vertebral region (e.g., lumbar plus sacral). M46.58 is appropriate only when infection is confined to the sacral or sacrococcygeal segment.
05Does M46.58 require a 7th-character extension?
No. M46.58 is a 6-character M-code with no 7th-character extension requirement. Seven-character extensions (A, D, S) apply to injury S-codes, not to musculoskeletal disease codes in Chapter 13.
06Which MS-DRGs does M46.58 map to in FY2026?
M46.58 groups into MS-DRG 456, 457, or 458 when paired with a spinal fusion procedure (severity-tiered by MCC/CC), and into MS-DRG 551 or 552 for medical management without fusion. Accurate site coding affects DRG weight assignment.
07Is M46.58 appropriate for post-procedural sacral wound infections that extend to bone?
Post-procedural infection codes (T84.6x or T81.4x) typically take sequencing priority when there is a clear link to a prior procedure. M46.58 may be added as an additional code to specify the anatomical involvement, but the post-procedural complication code should lead.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (effective Oct 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M45-M49/M46-/M46.58
  3. 03
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M46.58
  4. 04
    cms.gov
    https://www.cms.gov/medicare/coding-billing/icd-10-codes
  5. 05MS-DRG Grouper v43.0 — CMS

Mira AI Scribe

Mira AI Scribe captures the documented anatomical site (sacral vs. sacrococcygeal vs. lumbosacral), the identified or suspected pathogen, supporting lab values (ESR, CRP, blood/tissue cultures), and relevant imaging characterization (MRI signal changes, CT biopsy findings) from the encounter note. This prevents downcoding to M46.50 (unspecified site) or miscoding to the lumbosacral sibling M46.57, both of which can trigger payer audits and misrepresent DRG severity.

See how Mira captures M46.58 documentation

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