ICD-10-CM · Spine

M46.38

Pyogenic (bacterial) infection of the intervertebral disc located at the sacral or sacrococcygeal spinal level, classified under other inflammatory spondylopathies.

Verified May 8, 2026 · 3 sources ↓

Status
Billable
Chapter
13
Related CPT
5
Region
Spine
Drawn from CDCICD10DataAAPC

Documentation tips

What should appear in the chart to support M46.38.

Source · Editorial brief grounded in 3 cited references ↓

  • Explicitly state 'sacral' or 'sacrococcygeal' region in the assessment — vague 'lower spine' language forces the coder to default to an unspecified level.
  • Record the causative organism by name or by culture result so the required B95–B97 secondary code can be assigned accurately.
  • Document imaging findings that support infection: MRI signal changes, end-plate erosion, disc space narrowing, or paraspinal soft-tissue involvement.
  • Note pertinent risk factors (IV drug use, recent spinal procedure, immunosuppression, diabetes) as separately coded comorbidities — they support medical necessity for advanced imaging and inpatient admission.
  • If the infection spans more than one spinal region, document each affected level clearly so the correct multi-site or individual region codes can be assigned.

Related CPT procedures

Procedure codes commonly billed with M46.38. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M46.38 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Assigning M46.38 without a companion B95–B97 organism code violates the mandatory 'Use additional code' instruction at the M46.3 parent level — expect a claim edit or audit flag.
  • Using M46.38 for non-pyogenic disc infections (tuberculous, fungal) is incorrect; those infections have distinct codes (e.g., A18.01 for tuberculosis of spine).
  • Defaulting to M46.40 (discitis, unspecified, site unspecified) when the record clearly documents a pyogenic etiology and sacral location — this undercodes a confirmed, site-specific diagnosis.
  • Confusing the sacral region (M46.38) with the lumbosacral region (M46.37); verify the documented level against imaging before finalizing the code.

Clinical context

Source · Editorial summary grounded in 3 cited references ↓

M46.38 is the billable code for a pyogenic discitis confined to the sacral and sacrococcygeal region. It sits under parent code M46.3 (non-billable), which carries a mandatory 'Use additional code (B95–B97)' instruction — you must append a secondary code identifying the causative organism (e.g., B95.61 for MRSA, B96.20 for unspecified E. coli). Failing to add that organism code violates the tabular instruction and creates an audit vulnerability.

Sacrococcygeal disc infections are uncommon but serious, often presenting with severe low back or coccygeal pain, fever, and elevated inflammatory markers (ESR, CRP). MRI is the gold-standard imaging modality; disc space narrowing, end-plate erosion, and signal changes on T2-weighted sequences support the diagnosis. Patients may have risk factors including IV drug use, recent spinal procedure, diabetes, or immunosuppression — document these comorbidities separately.

Do not use M46.38 when the infection spans multiple spinal regions; in that case M46.39 (multiple sites) or separate region-specific codes may be appropriate. If the etiology is non-pyogenic (e.g., tuberculous), look to M49.8- or A18.01 instead. Discitis of unspecified type without confirmed infection belongs under M46.4x, not M46.3x.

Sibling codes

Other billable codes under M46.3 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 3 cited references ↓

01Is a secondary organism code really required with M46.38?
Yes. The M46.3 parent carries a tabular 'Use additional code (B95–B97) to identify infectious agent' instruction. Submitting M46.38 alone violates that convention. Assign the appropriate B95–B97 code based on culture results or documented clinical determination of the organism.
02What is the difference between M46.38 and M46.37?
M46.37 specifies pyogenic disc infection at the lumbosacral region; M46.38 specifies the sacral and sacrococcygeal region. The distinction hinges on the anatomic level documented in the clinical note or confirmed on imaging — do not assume interchangeability.
03Can M46.38 be used for tuberculous or fungal discitis?
No. M46.38 is restricted to pyogenic (bacterial) infections. Tuberculous spondylodiscitis is coded to A18.01 (tuberculosis of spine). Fungal or other non-pyogenic disc infections require review of M49.8- and related categories.
04What imaging supports the M46.38 diagnosis for coding purposes?
MRI is the standard. Document T2 hyperintensity within the disc, end-plate erosion or destruction, and any paraspinal or epidural abscess extension. Bone scan findings or CT evidence of end-plate destruction also support the diagnosis if MRI is contraindicated.
05Should M46.38 or M46.40 be used when the type of discitis is uncertain?
Use M46.40 (discitis, unspecified, site unspecified) or the site-specific M46.48 (sacral/sacrococcygeal) only when the etiology is genuinely undetermined. Once pyogenic infection is confirmed clinically or by culture, M46.38 with a B95–B97 organism code is correct and required.
06What CPT procedures are commonly reported alongside M46.38?
Spinal MRI without and with contrast (72148, 72158) is typical for diagnosis and follow-up. Aspiration or biopsy of the disc space (62267) and spinal surgical debridement or fusion (22899) may apply when operative intervention is required. Image-guided biopsy codes may also apply depending on technique and payer policy.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (effective October 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M45-M49/M46-/M46.38
  3. 03
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M46.38

Mira AI Scribe

Mira AI Scribe captures the documented spinal level (sacral/sacrococcygeal), confirmed pyogenic etiology, causative organism from culture or empiric clinical determination, MRI findings (end-plate erosion, T2 signal change, disc space narrowing), and relevant risk factors. This prevents the common failure of submitting M46.38 without the mandatory B95–B97 organism code, which triggers an edit, and avoids downgrading to unspecified discitis (M46.40) when full specificity is supported by the record.

See how Mira captures M46.38 documentation

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