ICD-10-CM · Spine

M46.36

Pyogenic (bacterial) infection of one or more intervertebral discs in the lumbar spine region, classified under other inflammatory spondylopathies.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
10
Region
Spine
Drawn from CDCICD10DataAAPCCMSIcdcodes

Documentation tips

What should appear in the chart to support M46.36.

Source · Editorial brief grounded in 5 cited references ↓

  • Specify 'lumbar region' by name and, where possible, the level(s) affected (e.g., L3–L4, L4–L5) to support medical necessity and site specificity.
  • Record MRI findings explicitly: T2 hyperintensity in the disc, endplate erosion, and any adjacent vertebral or paraspinal involvement.
  • Document inflammatory markers at the time of diagnosis — ESR and CRP values — to substantiate the infectious etiology and severity.
  • Identify the causative organism and assign the appropriate B95–B97 code; if cultures are pending, note this in the record and update coding when results return.
  • Distinguish whether infection is limited to the disc (M46.36) or has extended to the vertebral body (add M46.26) or formed an abscess (reassess for spondylitis codes), and document accordingly.
  • For inpatient cases, the MS-DRG assignment (539–541 Osteomyelitis; 456–458 Spinal Fusion with infection) is driven by MCC/CC status — document comorbidities that qualify as MCC or CC to ensure accurate DRG weight.

Related CPT procedures

Procedure codes commonly billed with M46.36. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

22630 $1,510.72
Posterior interbody arthrodesis of a single lumbar interspace, including laminectomy and/or discectomy performed to prepare the interspace for fusion rather than for decompression.
22612 $1,467.64
Posterior or posterolateral lumbar arthrodesis of a single interspace, performed via a posterior approach with bone graft and typically pedicle screw fixation to achieve vertebral segment fusion.
22558 $1,423.88
Anterior interbody arthrodesis of the lumbar spine using an anterior or anterolateral approach, including the minimal discectomy required to prepare the interspace for fusion.
22800 $1,312.99
Posterior spinal arthrodesis for deformity correction spanning up to 6 vertebral segments, with or without application of a body cast.
72148 $191.72
Non-contrast MRI of the lumbar spine used to evaluate disc pathology, spinal stenosis, nerve root compression, and other structural abnormalities without administration of contrast material.
72141 $190.72
MRI of the cervical spinal canal and its contents performed without contrast material.
20225 $364.74
Percutaneous bone biopsy using a trocar or needle targeting deep skeletal structures such as the vertebral body or femur.
22103 $115.90
Add-on code for each additional vertebral segment addressed during posterior or posterolateral partial excision of a bony lesion, reported alongside a primary segment code.
63030 $898.15
Single-interspace lumbar laminotomy with nerve root decompression, including partial facetectomy, foraminotomy, and/or herniated disc excision performed via open surgical technique.
62323 View procedure details

Common coding pitfalls

The recurring mistakes coders make with M46.36 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Assigning M46.36 without the required additional B95–B97 organism code violates the tabular 'Use additional code' instruction and invites a claim edit.
  • Using M54.5 (low back pain) or M46.46 (discitis, unspecified, lumbar region) when pyogenic infection is confirmed — M46.36 is the more specific, higher-acuity code and must be used when bacterial etiology is documented.
  • Confusing lumbar (M46.36) with lumbosacral (M46.37) — if the infected disc is at L5–S1, code M46.37, not M46.36.
  • Failing to add M46.26 when imaging also shows lumbar vertebral osteomyelitis — disc infection and vertebral osteomyelitis are coded separately and both should be reported.
  • Coding M46.36 for tuberculous or fungal discitis — those infections are classified in M49.0 (spondylopathy in infectious and parasitic diseases) or other category codes; M46.3x is pyogenic (bacterial) only.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M46.36 codes a confirmed pyogenic infection of the lumbar intervertebral disc — commonly called lumbar infectious discitis or pyogenic lumbar discitis. Apply it when the clinical picture includes bacterial disc infection at the lumbar level (L1–L5), supported by imaging (MRI T2 hyperintensity with endplate erosion) and/or laboratory markers (elevated ESR, CRP) or positive cultures. This code does NOT cover non-pyogenic (e.g., tuberculous) disc infections, which belong elsewhere in M46.

The ICD-10-CM tabular instruction at the M46.3 parent level requires you to assign an additional code from B95–B97 to identify the causative infectious agent (e.g., B95.62 for MRSA, B96.20 for unspecified E. coli). Skipping this secondary code is a documentation and compliance gap. If the organism is not yet identified at the time of coding, document that cultures are pending and add the organism code once results are available.

When infection extends into adjacent vertebral bone, code M46.26 (osteomyelitis of vertebra, lumbar region) concurrently. If there is adjacent abscess or pus formation confirmed on imaging or biopsy, consider whether M46.37 (lumbosacral) or a pyogenic spondylitis code better reflects the full extent of disease. For lumbar spinal fusion performed in the context of this infection, M46.36 is listed as a supporting medical necessity code under CMS LCD A56396.

Sibling codes

Other billable codes under M46.3 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01Do I always need to add a B95–B97 code when billing M46.36?
Yes. The M46.3 parent category carries a mandatory 'Use additional code (B95–B97) to identify infectious agent' instruction. Submitting M46.36 alone is non-compliant. If the organism is unknown at time of billing, use B99.9 (unspecified infectious disease) and update when culture results are available.
02What is the difference between M46.36 and M46.46?
M46.36 is pyogenic (bacterial) discitis of the lumbar region; the etiology is specified as infectious and bacterial. M46.46 is discitis, unspecified — use it only when the disc inflammation cannot be attributed to a pyogenic process. When bacterial infection is confirmed or clinically established, M46.36 is required.
03Should I use M46.36 or M46.37 for an L5–S1 disc infection?
Use M46.37 (lumbosacral region) for L5–S1 involvement. M46.36 covers the lumbar region (L1–L5 discs). Laterality is not the distinguishing factor here — spinal region is. Document the specific disc level in the chart to support whichever code you assign.
04Can M46.36 be used as the primary diagnosis for lumbar spinal fusion?
Yes. CMS LCD A56396 (Lumbar Spinal Fusion, article 56396) explicitly lists M46.36 as an ICD-10-CM code that supports medical necessity for lumbar spinal fusion. Ensure the operative note documents that the fusion is indicated by the infectious process.
05What MS-DRGs does M46.36 map to?
Under MS-DRG v43.0, M46.36 groups to DRGs 539–541 (Osteomyelitis with MCC/CC/without) when managed medically, and to DRGs 456–458 (Spinal Fusion except cervical with infection) when surgical fusion is performed. Final DRG depends on documented MCC and CC comorbidities.
06Does M46.36 require a 7th-character extension?
No. M46.36 is an M-code (musculoskeletal disease code), not a trauma S-code. It is a 6-character billable code with no 7th-character extension required or available.
07When should I add M46.26 alongside M46.36?
Add M46.26 (osteomyelitis of vertebra, lumbar region) whenever imaging or pathology confirms that the infection has extended from the disc into the adjacent vertebral body — a common progression in lumbar pyogenic discitis. The two conditions are distinct diagnoses and should both be coded.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (effective Oct 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M45-M49/M46-/M46.36
  3. 03
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M46.36
  4. 04
    cms.gov
    https://www.cms.gov/medicare-coverage-database/view/article.aspx?articleid=56396
  5. 05
    icdcodes.ai
    https://icdcodes.ai/icd10/M46.36

Mira AI Scribe

Mira AI Scribe captures lumbar-level documentation critical for M46.36: the specific disc level(s) involved, MRI findings (T2 signal change, endplate erosion, paraspinal or epidural involvement), ESR/CRP values, culture results or pending status, and the identified or suspected organism. This prevents the two most common gaps — missing the B95–B97 organism code and undercoding to M54.5 or M46.46 — which can trigger claim edits, reduce reimbursement, and create compliance exposure.

See how Mira captures M46.36 documentation

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