ICD-10-CM · Spine

M46.30

Pyogenic (bacterial) infection of an intervertebral disc where the spinal region has not been documented or specified by the treating provider.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
11
Region
Spine
Drawn from CDCICD10DataAAPCNIH

Documentation tips

What should appear in the chart to support M46.30.

Source · Editorial brief grounded in 5 cited references ↓

  • Specify the spinal region by name (cervical, thoracic, lumbar, etc.) in every note so a site-specific code (M46.31–M46.39) can be used instead of the unspecified M46.30.
  • Always document the causative organism when identified — culture results, blood culture reports, or biopsy pathology — and add the corresponding B95–B97 code as instructed by the ICD-10-CM Tabular List.
  • Distinguish pyogenic (bacterial) from non-pyogenic discitis in the assessment: the word 'pyogenic' or documentation of a specific bacterial agent supports M46.30–M46.39 over M46.4x.
  • Record imaging findings (MRI signal changes at the disc and adjacent endplates, gadolinium enhancement, CT evidence of endplate destruction) to support medical necessity for both the diagnosis and any surgical intervention.
  • Document conservative treatment history (antibiotics, duration, response) prior to any surgical procedure to satisfy payer medical necessity criteria.

Related CPT procedures

Procedure codes commonly billed with M46.30. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

22010 $950.92
Open incision and drainage of a deep subfascial abscess located along the posterior cervical, thoracic, or cervicothoracic spine
22015 $921.86
Open incision and drainage of a deep subfascial abscess along the posterior lumbar, sacral, or lumbosacral spine.
22554 $1,215.79
Anterior interbody arthrodesis of the cervical spine below C2, performed via anterior approach with minimal diskectomy to prepare the interspace for fusion — not performed for decompression purposes.
22558 $1,423.88
Anterior interbody arthrodesis of the lumbar spine using an anterior or anterolateral approach, including the minimal discectomy required to prepare the interspace for fusion.
22612 $1,467.64
Posterior or posterolateral lumbar arthrodesis of a single interspace, performed via a posterior approach with bone graft and typically pedicle screw fixation to achieve vertebral segment fusion.
22630 $1,510.72
Posterior interbody arthrodesis of a single lumbar interspace, including laminectomy and/or discectomy performed to prepare the interspace for fusion rather than for decompression.
63030 $898.15
Single-interspace lumbar laminotomy with nerve root decompression, including partial facetectomy, foraminotomy, and/or herniated disc excision performed via open surgical technique.
63047 $1,065.49
Lumbar laminectomy at a single vertebral segment that also includes facetectomy and foraminotomy for decompression of the spinal cord, cauda equina, and/or nerve roots — unilateral or bilateral.
72148 $191.72
Non-contrast MRI of the lumbar spine used to evaluate disc pathology, spinal stenosis, nerve root compression, and other structural abnormalities without administration of contrast material.
72158 $318.31
MRI of the lumbar spinal canal and its contents performed first without contrast, then repeated after contrast administration for enhanced visualization.
77080 View procedure details

Common coding pitfalls

The recurring mistakes coders make with M46.30 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Using M46.30 (site unspecified) when MRI or operative reports clearly identify the affected level — always assign the site-specific code (M46.31–M46.39) when level is documented.
  • Confusing M46.30 with M46.4 (discitis, unspecified): M46.30 requires documented or suspected pyogenic (bacterial) etiology; M46.4x is for discitis of unknown or unspecified cause.
  • Omitting the B95–B97 causative-agent code when the organism is identified — the Tabular List 'Use Additional' instruction at the M46.3 parent level makes this mandatory, not optional.
  • Coding M46.30 when M46.39 (multiple sites) is correct — if imaging or the operative report describes involvement at more than one spinal level, use M46.39.
  • Billing M46.30 on a claim for a spinal procedure without supporting imaging or culture documentation, which can trigger a medical necessity audit.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M46.30 is the fallback code within the M46.3 family when the operative report, clinic note, or imaging report does not identify which spinal region is involved. Use it only when level documentation is genuinely absent — not as a default when the provider simply hasn't been queried. The M46.3x subcategory spans occipito-atlanto-axial (M46.31) through sacral/sacrococcygeal (M46.38) and multi-site (M46.39); if any of those apply, they supersede M46.30.

Pyogenic disc infections — also called infectious discitis or septic discitis — are typically caused by hematogenous spread of Staphylococcus aureus, Streptococcus species, gram-negative rods, or other organisms. The ICD-10-CM Tabular List instructs coders to append an additional code from B95–B97 to identify the causative organism whenever it is documented. Failure to add the causative-agent code is a compliance gap, not a coder preference.

M46.30 sits under 'Other inflammatory spondylopathies' (M46), which is distinct from M46.4 (discitis, unspecified) — a non-pyogenic, cause-unknown category. If the provider has not confirmed a bacterial etiology, M46.4x may be more accurate. Do not use M46.30 interchangeably with M46.4x; the pyogenic qualifier requires clinical or microbiological support in the documentation.

Sibling codes

Other billable codes under M46.3 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01When is M46.30 appropriate versus a site-specific code like M46.36 (lumbar)?
Use M46.30 only when the spinal region genuinely cannot be determined from available documentation. If MRI, CT, or the operative report identifies the level, assign the matching site-specific code (M46.31–M46.38) or M46.39 for multiple sites.
02Do I need to add a second code when billing M46.30?
Yes, when the causative organism is documented. The ICD-10-CM Tabular List instructs coders to add a B95–B97 code (e.g., B95.61 for MRSA, B96.20 for unspecified E. coli) to identify the infectious agent. Omitting it is a coding deficiency.
03What is the difference between M46.30 and M46.4x?
M46.30–M46.39 specifies pyogenic (bacterial) disc infection; M46.40–M46.49 codes discitis of unspecified or unknown cause. Use M46.30 only when documentation supports a bacterial etiology. When the provider documents 'discitis' without specifying pyogenic or bacterial origin, M46.4x is more accurate.
04Can M46.30 be used as a primary diagnosis on a surgical claim for debridement or spinal fusion?
Yes, M46.30 can serve as the principal diagnosis supporting spinal debridement (22010, 22015) or instrumented fusion when the infection is the operative indication. Confirm that clinical documentation — imaging, culture data, failed antibiotic therapy — substantiates medical necessity for the level of surgery billed.
05Is M46.30 valid for FY2026 claims?
Yes. M46.30 is an active, billable ICD-10-CM code effective October 1, 2025 under the FY2026 code set, per the CDC ICD-10-CM Tabular List 2026.
06Should I use M46.30 if the patient has septic discitis at L4-L5 confirmed on MRI?
No. L4-L5 is in the lumbar region, so M46.36 (lumbar) is the correct code. M46.30 is reserved for cases where the spinal region is truly unspecified in the documentation.

Mira AI Scribe

Mira's AI scribe captures the spinal region involved, MRI or CT findings (endplate erosion, disc space signal changes, paraspinal abscess), culture or blood culture organism results, antibiotic course details, and whether the infection spans multiple levels. That documentation enables assignment of a site-specific M46.3x code and the required B95–B97 organism code — preventing a site-unspecified default that payers flag for additional documentation on high-cost spine claims.

See how Mira captures M46.30 documentation

Related ICD-10 codes

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