ICD-10-CM · Spine

M43.16

M43.16 identifies acquired or degenerative forward (or backward) slippage of a lumbar vertebra — distinct from congenital spondylolisthesis and from lumbosacral-level slippage coded separately at M43.17.

Verified May 8, 2026 · 6 sources ↓

Status
Billable
Chapter
13
Related CPT
14
Region
Spine
Drawn from CDCICD10DataAAPCIcdcodesOutsourcestrategies

Documentation tips

What should appear in the chart to support M43.16.

Source · Editorial brief grounded in 6 cited references ↓

  • Specify the lumbar spinal level(s) involved (e.g., L4–L5) — 'lumbar spondylolisthesis' alone supports M43.16, but level documentation strengthens medical necessity.
  • Document the Meyerding grade (I–IV) or percentage of slip; payers and surgical authorization teams require severity grading.
  • State the etiology when known: degenerative, isthmic (pars defect), traumatic (remote/healed), or iatrogenic — this differentiates from acute traumatic codes and congenital Q76.2.
  • Record imaging type, date, and key finding (e.g., 'Standing lateral lumbar X-ray shows Grade II anterolisthesis at L4–L5 with approximately 30% slip').
  • If flexion-extension instability is present, note it explicitly — it affects surgical candidacy and supports higher-intensity procedure authorization.
  • Document conservative care history (PT, NSAIDs, injections) before surgical claims to satisfy step-therapy requirements.

Related CPT procedures

Procedure codes commonly billed with M43.16. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

72100 $40.42
Radiologic examination of the lumbosacral spine capturing two or three views, used to evaluate the lumbar vertebrae and sacrum for injury, degeneration, or structural abnormality.
72110 $53.44
Radiologic examination of the lumbar spine (lumbosacral) with a minimum of four views, including oblique and/or bending views.
72114 $61.79
Radiologic examination of the lumbosacral spine, complete series with bending (flexion/extension) views — minimum of 6 views total.
72148 $191.72
Non-contrast MRI of the lumbar spine used to evaluate disc pathology, spinal stenosis, nerve root compression, and other structural abnormalities without administration of contrast material.
72141 $190.72
MRI of the cervical spinal canal and its contents performed without contrast material.
72158 $318.31
MRI of the lumbar spinal canal and its contents performed first without contrast, then repeated after contrast administration for enhanced visualization.
22612 $1,467.64
Posterior or posterolateral lumbar arthrodesis of a single interspace, performed via a posterior approach with bone graft and typically pedicle screw fixation to achieve vertebral segment fusion.
22630 $1,510.72
Posterior interbody arthrodesis of a single lumbar interspace, including laminectomy and/or discectomy performed to prepare the interspace for fusion rather than for decompression.
22633 $1,700.11
Single-level lumbar arthrodesis combining posterior or posterolateral technique with posterior interbody technique, including laminectomy and/or discectomy sufficient to prepare the interspace — performed as one surgical session at one lumbar interspace.
22840 $668.35
Posterior non-segmental instrumentation placed during spinal surgery, using rods, hooks, or wires that span multiple vertebral levels without anchoring at each intervening segment.
27096 $175.69
Injection into the sacroiliac joint with fluoroscopic or CT image guidance, including arthrography when performed.
97110 $29.06
Therapeutic exercise billed per 15-minute unit, targeting strength, endurance, range of motion, or flexibility with direct one-on-one patient contact.
62323 View procedure details
97012 View procedure details

Common coding pitfalls

The recurring mistakes coders make with M43.16 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Coding M43.16 for L5–S1 slippage — that level is the lumbosacral region; use M43.17 instead.
  • Using M43.16 for acute traumatic spondylolisthesis — acute injury at the lumbosacral region codes to S33.1, and acute fracture-related slippage at other sites codes to the appropriate vertebral fracture code.
  • Confusing spondylolisthesis (M43.16) with spondylolysis (M43.06) — a pars defect without measurable vertebral slip is spondylolysis; document both if both are confirmed.
  • Defaulting to M43.10 (site unspecified) when the operative or imaging report clearly names a lumbar level — unspecified codes invite payer scrutiny and downcoding.
  • Applying M43.16 to congenital spondylolisthesis — congenital cases require Q76.2, which is a Type 1 Excludes from the M43.1 family.

Clinical context

Source · Editorial summary grounded in 6 cited references ↓

Use M43.16 when imaging confirms vertebral slippage within the lumbar region (typically L1–L4/L5 level involvement) and the etiology is acquired — degenerative, isthmic, or iatrogenic. Do not use it for L5–S1 slippage; that junction is the lumbosacral region and belongs under M43.17. If the operative or diagnostic report specifies L5–S1 or 'lumbosacral,' switch codes.

M43.16 sits under the parent M43.1 (Spondylolisthesis), which carries two critical Type 1 Excludes notes: acute traumatic lumbosacral spondylolisthesis codes to S33.1, and congenital spondylolisthesis codes to Q76.2. Neither of those belongs under M43.16. Distinguish spondylolisthesis (vertebral body slippage) from spondylolysis (pars interarticularis defect without slip, M43.06) — the conditions can coexist but are coded separately when both are documented.

Common clinical scenarios for M43.16 include degenerative Grade I–II anterolisthesis at L4–L5 identified on standing lateral X-ray, isthmic spondylolisthesis in an active adult with pars defect, and retrolisthesis at a mid-lumbar level. Meyerding grade (I–IV), imaging modality, and spinal level should appear in the note to support medical necessity for conservative care, injections, or surgical referral.

Sibling codes

Other billable codes under M43.1 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 6 cited references ↓

01What is the difference between M43.16 and M43.17?
M43.16 covers spondylolisthesis in the lumbar region (typically L1–L5 involvement). M43.17 covers the lumbosacral region, specifically L5–S1. If the note or imaging report says 'L5–S1' or 'lumbosacral,' use M43.17.
02Can M43.16 be used for anterolisthesis and retrolisthesis?
Yes. Both anterolisthesis (forward slip) and retrolisthesis (posterior slip) in the lumbar region map to M43.16. Document the direction of slip in the note to support clinical specificity, though ICD-10-CM does not subdivide by direction.
03Should M43.06 (spondylolysis, lumbar) and M43.16 be coded together when both are present?
Yes, when the record confirms both a pars defect (spondylolysis) and measurable vertebral slippage (spondylolisthesis) at the lumbar level, report M43.06 and M43.16 together. They describe distinct pathological findings.
04Is M43.16 appropriate after lumbar fusion if the listhesis was the indication for surgery?
Yes, M43.16 remains the appropriate diagnosis code on the surgical claim when spondylolisthesis is the documented indication. Post-operative visits for hardware follow-up may also carry M43.16 as the primary reason for care unless a fusion-related complication has replaced it.
05What CPT codes are most commonly paired with M43.16?
Imaging: 72100, 72110, 72114 (lumbar X-ray series), 72148/72158 (lumbar MRI). Surgery: 22612 (posterior lumbar fusion), 22630 (PLIF), 22633 (combined), 22840 (posterior instrumentation). Injections: 62323 (lumbar epidural), 27096 (SI joint). Therapy: 97110, 97012.
06Does M43.16 require a 7th character extension?
No. M43.16 is an M-code (musculoskeletal, non-traumatic). Seventh-character extensions (A, D, S for initial/subsequent/sequela) apply to S-codes (injury codes), not M-codes.
07How does M43.16 differ from M48.06 (spinal stenosis, lumbar) and M51.16 (degeneration of disc, lumbar)?
M43.16 requires documented vertebral body slippage. M48.06 codes canal narrowing without slippage, and M51.16 codes disc degeneration without a slip. All three can be coded together when each is independently documented and clinically relevant.

Mira AI Scribe

The Mira AI Scribe captures spinal level (e.g., L4–L5), Meyerding slip grade, imaging confirmation (X-ray or MRI date and key finding), direction of slip (antero- vs. retrolisthesis), and any documented instability on flexion-extension views. Capturing these elements at the point of care prevents a drop to M43.10 (unspecified), blocks a mismatch to M43.17 (lumbosacral), and ensures the claim carries the clinical specificity payers require for surgical or injection pre-authorization.

See how Mira captures M43.16 documentation

Related ICD-10 codes

Ready?

Ready to transform your orthopedic practice?

See how orthopedic practices are running documentation, billing, and operations on a single voice-first platform.

Get started for free