ICD-10-CM · Spine

M43.10

Acquired spondylolisthesis — forward or backward slip of one vertebra relative to an adjacent vertebra — with the affected spinal region not documented or not specified.

Verified May 8, 2026 · 6 sources ↓

Status
Billable
Chapter
13
Related CPT
14
Region
Spine
Drawn from CDCICD10DataAAPCIcdcodesOutsourcestrategies

Documentation tips

What should appear in the chart to support M43.10.

Source · Editorial brief grounded in 6 cited references ↓

  • Name the specific spinal region in every note — lumbar, lumbosacral, thoracic, etc. — so you never need M43.10 in the first place.
  • Record the vertebral levels involved (e.g., L4-L5) and the slip grade (Meyerding Grade I–IV) to support medical necessity for surgery or injection.
  • Reference the imaging modality and findings — X-ray flexion-extension, MRI, or CT — including the degree of anterolisthesis or retrolisthesis documented in the radiology report.
  • Distinguish degenerative, isthmic, and other etiologies in the clinical note; the ICD-10 M43.1x series does not capture etiology, but payer LCDs for fusion often require it in the narrative.
  • If the provider's note says only 'spondylolisthesis,' send a query before assigning M43.10 — the level is almost always identifiable on imaging already in the chart.

Related CPT procedures

Procedure codes commonly billed with M43.10. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

22612 $1,467.64
Posterior or posterolateral lumbar arthrodesis of a single interspace, performed via a posterior approach with bone graft and typically pedicle screw fixation to achieve vertebral segment fusion.
22630 $1,510.72
Posterior interbody arthrodesis of a single lumbar interspace, including laminectomy and/or discectomy performed to prepare the interspace for fusion rather than for decompression.
22633 $1,700.11
Single-level lumbar arthrodesis combining posterior or posterolateral technique with posterior interbody technique, including laminectomy and/or discectomy sufficient to prepare the interspace — performed as one surgical session at one lumbar interspace.
22558 $1,423.88
Anterior interbody arthrodesis of the lumbar spine using an anterior or anterolateral approach, including the minimal discectomy required to prepare the interspace for fusion.
22600 $1,282.93
Posterior or posterolateral cervical spinal fusion at a single interspace below C2, performed through a posterior approach to achieve bony arthrodesis.
22610 $1,255.54
Single-level posterior or posterolateral thoracic spine arthrodesis using a transverse process technique
22853 $228.80
Add-on code for inserting an interbody biomechanical device (e.g., synthetic cage or mesh) with integral anterior anchoring instrumentation into an intervertebral disc space, performed alongside interbody arthrodesis, reported once per interspace.
63030 $898.15
Single-interspace lumbar laminotomy with nerve root decompression, including partial facetectomy, foraminotomy, and/or herniated disc excision performed via open surgical technique.
63047 $1,065.49
Lumbar laminectomy at a single vertebral segment that also includes facetectomy and foraminotomy for decompression of the spinal cord, cauda equina, and/or nerve roots — unilateral or bilateral.
72100 $40.42
Radiologic examination of the lumbosacral spine capturing two or three views, used to evaluate the lumbar vertebrae and sacrum for injury, degeneration, or structural abnormality.
72110 $53.44
Radiologic examination of the lumbar spine (lumbosacral) with a minimum of four views, including oblique and/or bending views.
72148 $191.72
Non-contrast MRI of the lumbar spine used to evaluate disc pathology, spinal stenosis, nerve root compression, and other structural abnormalities without administration of contrast material.
27096 $175.69
Injection into the sacroiliac joint with fluoroscopic or CT image guidance, including arthrography when performed.
72131 View procedure details

Common coding pitfalls

The recurring mistakes coders make with M43.10 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Defaulting to M43.10 when the imaging report clearly states 'L4-L5 spondylolisthesis' — that maps to M43.16 (lumbar region), not the unspecified code.
  • Using M43.10 for congenital spondylolisthesis — that is excluded from M43.1x entirely and belongs under Q76.2.
  • Assigning M43.10 for an acute traumatic slip — acute traumatic lumbosacral spondylolisthesis requires S33.1xx (with appropriate 7th character); other acute traumatic sites require a vertebral fracture code.
  • Failing to update M43.10 to a site-specific code after a query or addendum is returned — the amended note controls the final code assignment.
  • Pairing M43.10 with a procedure code tied to a specific level (e.g., L5-S1 fusion CPT 22630) without reconciling the diagnosis level; this mismatch can trigger NCCI or payer edits.

Clinical context

Source · Editorial summary grounded in 6 cited references ↓

M43.10 is the unspecified-site fallback within the M43.1 spondylolisthesis family. Use it only when the operative report, imaging read, or clinical note genuinely omits the spinal region. If the record names any region — lumbar, lumbosacral, thoracic, cervical, etc. — assign the site-specific code (M43.11–M43.19) instead. Payers increasingly flag M43.10 as lacking specificity, and some will downcode or deny without a query response or amended note.

M43.10 covers acquired (non-congenital) spondylolisthesis. Three Excludes1 carve-outs apply to parent code M43.1: acute traumatic lumbosacral spondylolisthesis (S33.1), acute traumatic spondylolisthesis at other sites (code to vertebral fracture by region), and congenital spondylolisthesis (Q76.2). Do not use M43.10 for any of those presentations regardless of whether the site is specified.

In ICD-9, a single code (738.4) handled all acquired spondylolisthesis. ICD-10 expanded this to 10 site-specific codes plus M43.10 as the unspecified option. That expansion was deliberate — payers and quality programs now expect anatomic precision. Treating M43.10 as a routine default rather than a last resort creates audit exposure and undermines medical-necessity support for spine procedures and injections tied to a specific spinal level.

Sibling codes

Other billable codes under M43.1 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 6 cited references ↓

01When is it actually appropriate to use M43.10 instead of a site-specific code?
Only when no spinal region is documented anywhere in the record — including imaging reports — and a physician query has either been declined or is not feasible. It is a last resort, not a default.
02Does M43.10 cover both degenerative and isthmic spondylolisthesis?
Yes. The M43.1x subcategory does not differentiate by etiology. Both degenerative and isthmic (pars defect) varieties map here. Document etiology in the clinical narrative for payer medical-necessity review, especially for surgical authorization.
03What is the difference between M43.10 and M43.00?
M43.00 is spondylolysis (a pars interarticularis defect) with site unspecified. M43.10 is spondylolisthesis (actual vertebral slip) with site unspecified. Spondylolysis can be a precursor to spondylolisthesis but they are distinct diagnoses — code both only when both are documented.
04Can M43.10 be used for multilevel spondylolisthesis?
No. Multiple sites in the spine have their own code: M43.19. If the record documents slips at more than one level, use M43.19, not M43.10.
05Is congenital spondylolisthesis ever coded to M43.10?
No. Congenital spondylolisthesis is explicitly excluded from the entire M43.1 subcategory by an Excludes1 note at the M43.1 level. Use Q76.2 for congenital spondylolysis and spondylolisthesis.
06How does M43.10 interact with procedure codes for lumbar fusion?
A mismatch between an unspecified diagnosis (M43.10) and a level-specific procedure code (e.g., CPT 22630 for L5-S1 interbody fusion) can trigger payer edits or medical-necessity denials. Align the diagnosis to the operative level before billing.
07Should M43.10 be used when the provider documents 'low back pain with spondylolisthesis' without specifying a level?
Query the provider first. Imaging is nearly always in the chart and will identify the level. If a level is confirmed after query, update to the appropriate site-specific code. Assign M43.10 only if no level can be established after a good-faith query effort.

Mira AI Scribe

Mira AI Scribe captures the spinal level (e.g., L4-L5), slip grade, imaging modality and findings (anterolisthesis on MRI/CT/plain film), and any neurologic symptoms from the encounter note — converting a vague 'spondylolisthesis' into M43.16 or another site-specific code automatically. That specificity prevents claim denial, supports medical necessity for fusion or decompression, and closes the audit gap created by M43.10.

See how Mira captures M43.10 documentation

Related ICD-10 codes

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