ICD-10-CM · Spine

M43.01

Acquired spondylolysis (a defect or stress fracture of the vertebral arch) localized to the occipito-atlanto-axial region — the bony junction involving the occiput, atlas (C1), and axis (C2).

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
10
Region
Spine
Drawn from CDCICD10DataAAPCCMS

Documentation tips

What should appear in the chart to support M43.01.

Source · Editorial brief grounded in 5 cited references ↓

  • Specify the anatomical region explicitly — 'occipito-atlanto-axial' or 'C1-C2' — in the clinical note to support the site-specific code over M43.00 (unspecified site).
  • Document whether the spondylolysis is acquired vs. congenital; if congenital origin is suspected or confirmed, Q76.2 replaces M43.01.
  • Record imaging modality and findings — CT best characterizes the bony defect, and the report should describe the specific arch or pars defect at this level.
  • Note the presence or absence of associated instability or vertebral translation; if slip is documented, evaluate whether M43.11 (spondylolisthesis, occipito-atlanto-axial region) better captures the full picture.
  • Document symptom burden: neck pain, occipital neuralgia, myelopathic signs, or neurological deficits, which may affect medical necessity determinations for surgical procedures.

Related CPT procedures

Procedure codes commonly billed with M43.01. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M43.01 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Using M43.01 and M43.11 together on the same claim — the tabular Excludes1 note under M43.0 prohibits coding spondylolysis and spondylolisthesis at the same site simultaneously; choose the code that reflects the documented primary pathology.
  • Defaulting to M43.00 (unspecified site) when the provider has clearly documented involvement of the C1-C2 or craniocervical junction — always code to the highest documented specificity.
  • Coding M43.01 when the record supports a congenital defect — congenital spondylolysis maps to Q76.2, not M43.01.
  • Confusing this code with cervical region (M43.02) or cervicothoracic region (M43.03) — the occipito-atlanto-axial region is anatomically distinct and limited to the occiput-C1-C2 complex.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M43.01 codes acquired spondylolysis of the uppermost cervical spine, specifically the articulations between the occiput, C1 (atlas), and C2 (axis). This is an anatomically uncommon site for spondylolysis compared to the lumbar region, and its presence at this level raises concern for structural instability at the craniocervical junction. Use this code when imaging confirms a pars interarticularis defect or arch defect in this region and there is no documented congenital origin.

Do not use M43.01 for congenital spondylolysis — that belongs under Q76.2. There is also a Type 1 Excludes relationship between M43.0 (spondylolysis) and M43.1 (spondylolisthesis): if vertebral slippage is also present, code the spondylolisthesis separately using M43.11 for the same region; you cannot use both M43.01 and M43.11 on the same claim per the tabular excludes logic. If the defect is at a different cervical level (e.g., C2-C3 junction), M43.02 (cervical region) or M43.03 (cervicothoracic region) may be more accurate.

Clinical workup typically includes CT or MRI of the cervical spine and craniocervical junction to characterize the defect. Flexion-extension radiographs may be ordered to assess instability. Document whether the finding is incidental or symptomatic, as that distinction can affect medical necessity for advanced imaging and surgical consultation.

Sibling codes

Other billable codes under M43.0 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01What distinguishes M43.01 from M43.00?
M43.00 is the unspecified-site fallback and should only be used when the treating provider has not documented which spinal region is involved. If the record identifies the occiput-C1-C2 complex, M43.01 is required — payers increasingly reject unspecified codes when a specific site is apparent from the clinical note or imaging report.
02Can M43.01 and M43.11 be coded together for the same encounter?
No. The ICD-10-CM Tabular List places an Excludes1 note between M43.0 (spondylolysis) and M43.1 (spondylolisthesis), meaning they cannot be coded at the same site simultaneously. If both a pars defect and vertebral slip are documented at the occipito-atlanto-axial region, code the dominant or treated condition and query the provider if needed.
03Is Q76.2 ever the right code instead of M43.01?
Yes. Q76.2 (congenital spondylolisthesis/spondylolysis) applies when the defect is developmental rather than acquired. If imaging or clinical notes describe the finding as congenital or the patient has a pediatric history of the anomaly, Q76.2 supersedes M43.01 per the Excludes1 note under M43.0.
04What imaging best supports M43.01 for documentation purposes?
CT of the cervical spine or craniocervical junction provides the clearest characterization of a bony arch defect at the C1-C2 level. MRI adds soft-tissue and cord detail. Flexion-extension radiographs document instability. The imaging report should explicitly describe the pars or arch defect at the occipito-atlanto-axial region to anchor the diagnosis code.
05Which CPT codes commonly pair with M43.01 in an orthopedic or spine practice?
Diagnostic imaging codes 72125–72127 (CT cervical spine without, with, or without/with contrast) and 72141/72148 (MRI cervical spine) are frequent companions. Surgical procedures such as 22595 (arthrodesis, posterior, C1-C2) or 22600 (arthrodesis, anterior, C2-C3) may be indicated if instability is confirmed. Always verify medical necessity linkage between the procedure and the diagnosis.
06Is M43.01 valid for FY2026 billing?
Yes. M43.01 is a billable, specific code in the FY2026 ICD-10-CM Tabular List (effective October 1, 2025) and has been valid since the ICD-10-CM implementation in 2016 without structural change to this code.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (FY2026, effective October 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M40-M43/M43-/M43.01
  3. 03
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M40-M43/M43-/M43.1
  4. 04
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M43
  5. 05
    cms.gov
    https://www.cms.gov/medicare/coding-billing/icd-10-codes

Mira AI Scribe

Mira AI Scribe captures the specific spinal level (occiput, C1, C2), imaging findings confirming the arch or pars defect, onset context (acquired vs. congenital), and presence or absence of vertebral translation. This prevents a drop to unspecified M43.00, avoids a congenital misclassification to Q76.2, and flags when concurrent spondylolisthesis documentation would require a coding review.

See how Mira captures M43.01 documentation

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