ICD-10-CM · Multi-region

M35.7

M35.7 classifies hypermobility syndrome — a connective tissue condition characterized by excessive joint laxity beyond normal range, often associated with chronic pain, recurrent subluxations, and generalized ligamentous laxity including familial ligamentous laxity.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
10
Region
Multi-region
Drawn from CDCICD10DataEhlers-danlosCMSAAPC

Documentation tips

What should appear in the chart to support M35.7.

Source · Editorial brief grounded in 5 cited references ↓

  • Record a Beighton score (0–9) with specific positive findings (e.g., thumb-to-forearm, elbow/knee hyperextension) to support the hypermobility diagnosis and distinguish it from EDS criteria.
  • Explicitly state whether systemic features of Ehlers-Danlos syndrome are absent — this protects the M35.7 selection and satisfies the Type 1 Excludes rule.
  • Document recurrent joint events by site and frequency (e.g., 'patellar subluxations x3 in past year, bilateral') to justify associated joint-specific codes billed alongside M35.7.
  • If using M35.7 as a proxy for hypermobility spectrum disorder (HSD), note that in the record — HSD has no dedicated ICD-10-CM code, and M35.7 is the accepted clinical workaround.
  • Capture functional impact and conservative care history (PT, bracing, prior imaging) to support medical necessity for orthopedic evaluation and therapeutic services.

Related CPT procedures

Procedure codes commonly billed with M35.7. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M35.7 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Billing M35.7 and Q79.62 (hypermobile EDS) on the same claim violates the Type 1 Excludes rule — these codes can never be used together; choose one based on whether formal EDS criteria are met.
  • Using M35.7 for a localized hypermobile joint (e.g., a single hypermobile thumb) is a miscoding — M35.7 reflects a systemic or generalized syndrome, not isolated joint laxity.
  • Assuming M35.7 covers all connective tissue hypermobility without provider documentation of the syndrome; the diagnosis must be explicitly documented — 'loose joints' alone is insufficient.
  • Omitting secondary joint-specific codes (e.g., M25.5x for arthralgia, M25.3x for instability) when the orthopedic visit is driven by a specific joint complaint — M35.7 alone may not capture the full clinical picture.
  • Confusing the MS-DRG assignment: M35.7 maps to DRG 557/558 (Tendonitis, Myositis and Bursitis), which may surprise coders expecting a connective tissue DRG — verify payer grouper logic before submission.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M35.7 is the correct code when a provider documents hypermobility syndrome or familial ligamentous laxity as a standalone diagnosis. The Tabular List includes an 'Applicable To' note covering familial ligamentous laxity, so that variant does not need a separate code. This is a connective tissue classification under M35 (Other systemic involvement of connective tissue), not a joint-specific or injury code — no laterality character or 7th-character extension applies.

M35.7 carries a critical Type 1 Excludes relationship with Ehlers-Danlos syndrome (EDS), coded under Q79.60–Q79.69. These two codes must never appear on the same claim. If the provider documents confirmed hEDS (hypermobile EDS), use Q79.62 — not M35.7. M35.7 is appropriate when systemic features and family history required for a formal EDS diagnosis are absent. Clinicians frequently use M35.7 as a practical workaround for hypermobility spectrum disorder (HSD), since HSD has no dedicated ICD-10-CM code; that usage is clinically accepted but should be flagged in documentation.

For orthopedic encounters, M35.7 commonly appears alongside joint-specific codes such as M25.5x (arthralgia by site) or instability/subluxation codes when the hypermobility is driving the orthopedic complaint. Follow ICD-10-CM Official Guidelines Section I.C.15 for syndromes: code the documented manifestations when a syndrome code doesn't fully capture the clinical picture.

Inclusion & exclusion notes

Per the official ICD-10-CM Tabular List.

Source · CDC ICD-10-CM Official Tabular List · 2026

Includes

  • Familial ligamentous laxity

Excludes 1 — never code together

  • ligamentous laxity, NOS (M24.2-)

Excludes 2 — may coexist if both documented

  • Ehlers-Danlos syndromes (Q79.6-)

Sibling codes

Other billable codes under M35 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01Can M35.7 and Q79.62 (hypermobile EDS) be billed on the same claim?
No. M35.7 has a Type 1 Excludes note for Ehlers-Danlos syndrome (Q79.60–Q79.69). These codes can never appear together. Use Q79.62 only when the provider documents confirmed hEDS using the 2017 diagnostic criteria; use M35.7 when EDS criteria are not met.
02Is M35.7 the right code for hypermobility spectrum disorder (HSD)?
HSD has no dedicated ICD-10-CM code. Clinicians widely use M35.7 as a practical workaround, a practice endorsed by The Ehlers-Danlos Society. Document the HSD diagnosis explicitly in the record so the M35.7 selection is defensible on audit.
03Does M35.7 require a 7th-character extension?
No. M35.7 is a complete 4-character code. M-codes under Chapter 13 do not use 7th-character extensions (A/D/S). The code is billable as listed.
04Should joint-specific pain or instability codes be added alongside M35.7?
Yes, when the encounter addresses a specific joint complaint. M35.7 captures the systemic syndrome; codes like M25.5x (arthralgia by site) or M25.3x (instability) capture the joint-level findings driving the orthopedic visit. Code all documented conditions per ICD-10-CM guidelines.
05Can M35.7 be used for a single hypermobile joint rather than a generalized syndrome?
No. M35.7 represents a systemic or generalized connective tissue syndrome. Isolated hypermobility at a single joint should be coded with the appropriate joint-specific instability or laxity code, not M35.7.
06What DRG does M35.7 group into for inpatient claims?
Under MS-DRG v43.0, M35.7 groups into DRG 557 (Tendonitis, Myositis and Bursitis with MCC) or DRG 558 (without MCC). Verify this against your payer's grouper version, as the DRG assignment may affect expected reimbursement planning.
07What Beighton score threshold supports documenting hypermobility syndrome?
A score of 5 or higher (out of 9) is the commonly cited threshold for generalized joint hypermobility in adults, though clinical diagnosis also requires symptom correlation. Document the numeric score and each positive maneuver — 'loose joints' alone is insufficient for coding or audit defense.

Sources & references

Editorial content was developed using the following public sources. Last verified May 8, 2026.

  1. 01CDC ICD-10-CM Tabular List 2026 (FY2026, effective Oct 1, 2025)
  2. 02
    icd10data.com
    https://www.icd10data.com/ICD10CM/Codes/M00-M99/M30-M36/M35-/M35.7
  3. 03
    ehlers-danlos.com
    https://www.ehlers-danlos.com/icd-codes/
  4. 04
    cms.gov
    https://www.cms.gov/files/document/fy-2025-icd-10-cm-coding-guidelines.pdf
  5. 05
    aapc.com
    https://www.aapc.com/codes/icd-10-codes/M35.7

Mira AI Scribe

The Mira AI Scribe captures the Beighton score and specific positive maneuvers, affected joints with recurrence history, absence of systemic EDS features, imaging findings (joint effusion, instability on stress views), and prior conservative care. This prevents a downcode to an unspecified connective tissue code, blocks an inadvertent dual-coding violation with Q79.62, and ensures secondary joint-specific codes are supported for complete claim submission.

See how Mira captures M35.7 documentation

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