ICD-10-CM · General

M31.7

M31.7 identifies microscopic polyangiitis (MPA), a systemic ANCA-associated vasculitis targeting small vessels — and occasionally medium vessels — with a predilection for renal and pulmonary involvement.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
0
Region
General
Drawn from CDCICD10DataAAPCCdekNIH

Documentation tips

What should appear in the chart to support M31.7.

Source · Editorial brief grounded in 5 cited references ↓

  • Confirm the specific diagnosis as microscopic polyangiitis — not simply 'ANCA vasculitis' or 'polyarteritis' — before assigning M31.7; the Alphabetic Index distinguishes these explicitly.
  • Document ANCA status (MPO-ANCA/p-ANCA positivity is typical for MPA) and the organs involved (kidneys, lungs, peripheral nerves, skin) to support medical necessity and specificity.
  • When MPA is causing a secondary condition (e.g., glomerulonephritis, polyneuropathy), sequence M31.7 as the underlying etiology and the manifestation code (e.g., N05.9, G62.9) as an additional diagnosis per etiology/manifestation convention.
  • Record immunosuppressive or biologic therapy in use — this affects surgical risk, infection risk coding, and prior authorization documentation for any concurrent procedures.
  • Distinguish MPA from granulomatosis with polyangiitis (M31.3-) and eosinophilic granulomatosis with polyangiitis (M30.1) in the clinical note; these are separate diagnoses with separate codes and cannot be coded concurrently with M31.7.

Common coding pitfalls

The recurring mistakes coders make with M31.7 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Assigning I77.82 (ANCA vasculitis) instead of M31.7 when the provider has documented a confirmed diagnosis of microscopic polyangiitis — I77.82 has a Type 2 Excludes note for M31.7 and should not be used when MPA is specified.
  • Confusing microscopic polyangiitis (M31.7) with polyarteritis nodosa (M30.0) — the Excludes1 note at M31.7 bars simultaneous coding; these are distinct entities and cannot be coded together.
  • Using M30.0 for a patient whose record says 'microscopic polyarteritis' — the Alphabetic Index directs 'microscopic polyarteritis' to M31.7, not M30.0.
  • Omitting manifestation codes for organ-specific complications (glomerulonephritis, polyneuropathy) when MPA is the underlying cause — the etiology/manifestation pair is required and improves clinical picture for payers.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M31.7 covers microscopic polyangiitis, also indexed as microscopic polyarteritis. This is a pauci-immune, ANCA-associated vasculitis of small vessels characterized by necrotizing inflammation without granuloma formation. Renal manifestations (rapidly progressive glomerulonephritis) and pulmonary capillaritis are the hallmark organ involvements, but peripheral neuropathy and skin findings are also coded back to M31.7 when caused by this condition.

The Excludes1 note at M31.7 prohibits simultaneous use with polyarteritis nodosa (M30.0) — these are mutually exclusive diagnoses. Separately, I77.82 (ANCA vasculitis) carries a Type 2 Excludes for M31.7, meaning I77.82 should not be assigned when MPA is the confirmed diagnosis; M31.7 is the more specific code. Do not default to I77.82 simply because ANCA positivity is documented — if the clinical diagnosis is MPA, use M31.7.

In an orthopedic or musculoskeletal practice, M31.7 surfaces most often as a comorbidity affecting treatment planning — for example, when immunosuppressive therapy for MPA complicates perioperative management, or when MPA-related arthropathy or myopathy is part of the presenting complaint. It sits within the systemic connective tissue disorders block (M30–M36), making it a valid diagnosis for rheumatology-adjacent encounters billed through orthopedic or connective tissue specialty practices.

Inclusion & exclusion notes

Per the official ICD-10-CM Tabular List.

Source · CDC ICD-10-CM Official Tabular List · 2026

Includes

  • Microscopic polyarteritis

Excludes 1 — never code together

  • polyarteritis nodosa (M30.0)

Sibling codes

Other billable codes under M31 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01What is the difference between M31.7 and I77.82 for ANCA-associated vasculitis?
I77.82 (ANCA vasculitis) is a general code with a Type 2 Excludes for M31.7. When the clinical diagnosis is specifically microscopic polyangiitis, assign M31.7 — it is more specific and takes precedence. Reserve I77.82 only for ANCA vasculitis cases where the provider has not specified a named subtype such as MPA, GPA, or EGPA.
02Can M31.7 and M30.0 be coded together on the same claim?
No. M31.7 carries an Excludes1 note referencing M30.0 (polyarteritis nodosa). These are mutually exclusive diagnoses and cannot be reported simultaneously per ICD-10-CM Tabular rules.
03How should I code renal involvement from MPA — do I use M31.7 alone?
Use M31.7 as the etiology code and add the appropriate manifestation code (e.g., N05.9 for unspecified nephritic syndrome) as an additional diagnosis. The Alphabetic Index under 'glomerulonephritis, in microscopic polyangiitis' cross-references this pairing.
04Where does M31.7 sit in the ICD-10-CM hierarchy?
M31.7 is a billable code under category M31 (Other necrotizing vasculopathies), within the Systemic connective tissue disorders block (M30–M36), Chapter 13 — Diseases of the musculoskeletal system and connective tissue (M00–M99), per the CDC ICD-10-CM Tabular List 2026.
05Is M31.7 valid for FY2026?
Yes. M31.7 is a valid, billable, and unchanged code in the FY2026 ICD-10-CM code set effective October 1, 2025, per the CDC ICD-10-CM Tabular List 2026.
06If a patient with MPA presents for an orthopedic procedure, should M31.7 be the principal diagnosis?
Generally no — sequence the condition chiefly responsible for the encounter (e.g., the musculoskeletal problem requiring surgery) as the principal diagnosis, and list M31.7 as a secondary comorbidity. However, if the encounter is specifically to manage the MPA or a direct MPA complication, M31.7 may be principal.
07Can I use M31.7 for polyneuropathy caused by microscopic polyangiitis?
Yes. The Alphabetic Index under 'polyneuropathy, in microscopic polyangiitis' directs to M31.7. Code M31.7 as the underlying etiology and add G62.9 (or a more specific polyneuropathy code if documented) as the manifestation diagnosis.

Mira AI Scribe

The Mira AI Scribe captures the confirmed MPA diagnosis, ANCA serotype (MPO vs. PR3), affected organ systems (renal, pulmonary, neurologic, cutaneous), current immunosuppressive regimen, and any biopsy or imaging findings supporting necrotizing vasculitis. This prevents assignment of the less-specific I77.82 or an incorrect M30.0, and ensures manifestation codes are paired correctly — avoiding a claim that understates disease severity or triggers a specificity audit.

See how Mira captures M31.7 documentation

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