ICD-10-CM · Knee

M22.40

Softening or breakdown of the cartilage on the underside of the kneecap, coded without specification of which knee is affected.

Verified May 8, 2026 · 5 sources ↓

Status
Billable
Chapter
13
Related CPT
5
Region
Knee
Drawn from CDCICD10DataAAPCOutsourcestrategiesNIH

Documentation tips

What should appear in the chart to support M22.40.

Source · Editorial brief grounded in 5 cited references ↓

  • Record the affected side by name (right or left) at every encounter — if laterality is known, M22.40 is the wrong code; use M22.41 or M22.42.
  • Document the Outerbridge grade or arthroscopic grading of cartilage damage if obtained; this supports medical necessity for surgical intervention and differentiates the diagnosis from nonspecific anterior knee pain.
  • Include MRI findings (cartilage signal change, fissuring, patellar tilt, trochlear morphology) or arthroscopic observation to substantiate the chondromalacia diagnosis rather than relying on symptom description alone.
  • Note the patient's conservative care history (physical therapy, NSAIDs, activity modification) before any surgical or procedural claim — payers commonly require documented failed conservative management.
  • If the reason laterality is unspecified is that the patient is being evaluated for bilateral symptoms before imaging, state that explicitly in the assessment to preempt an audit query.

Related CPT procedures

Procedure codes commonly billed with M22.40. Linking the right diagnosis to the right procedure is what establishes medical necessity.

Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis

Common coding pitfalls

The recurring mistakes coders make with M22.40 and adjacent codes.

Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓

  • Defaulting to M22.40 when laterality is documented in the note — always assign M22.41 (right) or M22.42 (left) when the side is known; unspecified codes can trigger payer edits and downcoding.
  • Confusing chondromalacia patellae (M22.4x) with patellofemoral disorder (M22.2Xx) — patellofemoral syndrome is a broader pain syndrome not synonymous with documented cartilage softening; use the code that matches the documented diagnosis.
  • Coding M22.40 alongside M22.90 (unspecified disorder of patella, unspecified knee) — these are redundant; pick the more specific chondromalacia code and drop the nonspecific one.
  • Failing to add a secondary diagnosis code for an underlying cause (e.g., patellar malalignment M22.2X9) when the provider documents one — chondromalacia is often secondary to tracking abnormalities that should also be coded.

Clinical context

Source · Editorial summary grounded in 5 cited references ↓

M22.40 applies when the provider documents chondromalacia patellae but does not specify right or left. Because laterality is a required element for specificity in the M22.4 family, use this code only when the operative or clinical note genuinely omits side — not as a shortcut. If the encounter note names the affected knee, step up to M22.41 (right) or M22.42 (left).

Chondromalacia patellae involves articular cartilage softening on the posterior patellar surface, producing anterior knee pain worsened by stairs, prolonged sitting, or squatting. It commonly appears in younger, active patients and is diagnosed through clinical exam (positive Clarke's sign, crepitus) and confirmed on MRI (Outerbridge grade I–IV) or at arthroscopy. The condition falls under Chapter 13, Diseases of the Musculoskeletal System and Connective Tissue (M00–M99), within the Other Joint Disorders block (M20–M25).

For billing, M22.40 groups into MS-DRG 562 (fracture, sprain, strain and dislocation except femur, hip, pelvis and thigh, with MCC) and 563 (without MCC) under v43.0. Payers may scrutinize the unspecified laterality, particularly when only one knee is treated — document why laterality was not recorded if that's genuinely the case.

Sibling codes

Other billable codes under M22.4 (laterality / anatomic variants).

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 5 cited references ↓

01When should I use M22.40 instead of M22.41 or M22.42?
Only when the clinical documentation genuinely does not specify which knee is affected. If the provider names the side anywhere in the note — including the physical exam or imaging section — assign M22.41 (right) or M22.42 (left) instead.
02Can M22.40 be used for bilateral chondromalacia?
No. There is no single bilateral code in the M22.4 family. Report M22.41 and M22.42 together for bilateral involvement, appending modifier 50 or separate line items per payer policy. M22.40 is unspecified laterality, not bilateral.
03What is the difference between M22.40 and M22.2X9 (patellofemoral disorder, unspecified knee)?
M22.2X9 covers patellofemoral pain syndrome — a clinical pain syndrome often without confirmed cartilage damage. M22.40 requires documented chondromalacia — confirmed softening or breakdown of patellar cartilage, ideally on MRI or arthroscopy. Code what the provider documents, not the symptom alone.
04Which CPT procedures most commonly link to M22.40?
Arthroscopic chondroplasty of the patella (29877), patellar arthroplasty with prosthesis (27438), and diagnostic knee imaging (73564) are the most common procedural pairings. Total knee arthroplasty (27447) may carry this diagnosis as a secondary finding when patellofemoral involvement is part of the overall degenerative picture.
05Does M22.40 require a 7th character?
No. M22.40 is an M-code (musculoskeletal disease code), not an S-code (injury code). Seventh-character extensions (A, D, S for initial, subsequent, sequela) do not apply. The code is complete as a six-character billable code.
06Is M22.40 valid for FY2026 claims?
Yes. M22.40 became effective October 1, 2015, has had no changes through FY2026, and remains a valid billable code under the 2026 ICD-10-CM edition effective October 1, 2025. Source: CDC ICD-10-CM Tabular List 2026.
07What imaging supports this diagnosis for audit purposes?
MRI is the preferred non-invasive study — look for documentation of cartilage signal abnormality, fissuring, or subchondral changes on the posterior patellar surface. Arthroscopic confirmation with Outerbridge grading (I–IV) is definitive. Document findings verbatim from the radiology or operative report to support medical necessity.

Mira AI Scribe

Mira's AI scribe captures the affected knee side, Outerbridge or MRI cartilage grade, physical exam findings (crepitus, Clarke's sign), and prior conservative treatment from the encounter note. That detail prevents the lateral upgrade from M22.40 to M22.41 or M22.42 from being missed and keeps the claim from stalling at payer edits for unspecified laterality.

See how Mira captures M22.40 documentation

Related ICD-10 codes

Ready?

Ready to transform your orthopedic practice?

See how orthopedic practices are running documentation, billing, and operations on a single voice-first platform.

Get started for free