Softening or breakdown of the cartilage on the underside of the kneecap, coded without specification of which knee is affected.
Verified May 8, 2026 · 5 sources ↓
- Status
- Billable
- Chapter
- 13
- Related CPT
- 5
- Region
- Knee
Documentation tips
What should appear in the chart to support M22.40.
Source · Editorial brief grounded in 5 cited references ↓
- Record the affected side by name (right or left) at every encounter — if laterality is known, M22.40 is the wrong code; use M22.41 or M22.42.
- Document the Outerbridge grade or arthroscopic grading of cartilage damage if obtained; this supports medical necessity for surgical intervention and differentiates the diagnosis from nonspecific anterior knee pain.
- Include MRI findings (cartilage signal change, fissuring, patellar tilt, trochlear morphology) or arthroscopic observation to substantiate the chondromalacia diagnosis rather than relying on symptom description alone.
- Note the patient's conservative care history (physical therapy, NSAIDs, activity modification) before any surgical or procedural claim — payers commonly require documented failed conservative management.
- If the reason laterality is unspecified is that the patient is being evaluated for bilateral symptoms before imaging, state that explicitly in the assessment to preempt an audit query.
Related CPT procedures
Procedure codes commonly billed with M22.40. Linking the right diagnosis to the right procedure is what establishes medical necessity.
Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis
Common coding pitfalls
The recurring mistakes coders make with M22.40 and adjacent codes.
Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓
- Defaulting to M22.40 when laterality is documented in the note — always assign M22.41 (right) or M22.42 (left) when the side is known; unspecified codes can trigger payer edits and downcoding.
- Confusing chondromalacia patellae (M22.4x) with patellofemoral disorder (M22.2Xx) — patellofemoral syndrome is a broader pain syndrome not synonymous with documented cartilage softening; use the code that matches the documented diagnosis.
- Coding M22.40 alongside M22.90 (unspecified disorder of patella, unspecified knee) — these are redundant; pick the more specific chondromalacia code and drop the nonspecific one.
- Failing to add a secondary diagnosis code for an underlying cause (e.g., patellar malalignment M22.2X9) when the provider documents one — chondromalacia is often secondary to tracking abnormalities that should also be coded.
Clinical context
Source · Editorial summary grounded in 5 cited references ↓
M22.40 applies when the provider documents chondromalacia patellae but does not specify right or left. Because laterality is a required element for specificity in the M22.4 family, use this code only when the operative or clinical note genuinely omits side — not as a shortcut. If the encounter note names the affected knee, step up to M22.41 (right) or M22.42 (left).
Chondromalacia patellae involves articular cartilage softening on the posterior patellar surface, producing anterior knee pain worsened by stairs, prolonged sitting, or squatting. It commonly appears in younger, active patients and is diagnosed through clinical exam (positive Clarke's sign, crepitus) and confirmed on MRI (Outerbridge grade I–IV) or at arthroscopy. The condition falls under Chapter 13, Diseases of the Musculoskeletal System and Connective Tissue (M00–M99), within the Other Joint Disorders block (M20–M25).
For billing, M22.40 groups into MS-DRG 562 (fracture, sprain, strain and dislocation except femur, hip, pelvis and thigh, with MCC) and 563 (without MCC) under v43.0. Payers may scrutinize the unspecified laterality, particularly when only one knee is treated — document why laterality was not recorded if that's genuinely the case.
Sibling codes
Other billable codes under M22.4 (laterality / anatomic variants).
Frequently asked questions
Source · Generated from the editorial pipeline, verified against 5 cited references ↓
01When should I use M22.40 instead of M22.41 or M22.42?
02Can M22.40 be used for bilateral chondromalacia?
03What is the difference between M22.40 and M22.2X9 (patellofemoral disorder, unspecified knee)?
04Which CPT procedures most commonly link to M22.40?
05Does M22.40 require a 7th character?
06Is M22.40 valid for FY2026 claims?
07What imaging supports this diagnosis for audit purposes?
Sources & references
Editorial content was developed using the following public sources. Last verified May 8, 2026.
- 01CDC ICD-10-CM Tabular List 2026 (effective Oct 1, 2025)
- 02icd10data.comhttps://www.icd10data.com/ICD10CM/Codes/M00-M99/M20-M25/M22-/M22.40
- 03aapc.comhttps://www.aapc.com/codes/icd-10-codes/M22.40
- 04outsourcestrategies.comhttps://www.outsourcestrategies.com/blog/patellofemoral-syndrome-coding-and-billing-guidelines/
- 05vsac.nlm.nih.govhttps://vsac.nlm.nih.gov/context/cs/codesystem/ICD10CM/version/2023/code/M22.40/info
Mira AI Scribe
Mira's AI scribe captures the affected knee side, Outerbridge or MRI cartilage grade, physical exam findings (crepitus, Clarke's sign), and prior conservative treatment from the encounter note. That detail prevents the lateral upgrade from M22.40 to M22.41 or M22.42 from being missed and keeps the claim from stalling at payer edits for unspecified laterality.
See how Mira captures M22.40 documentation