Secondary gout involving multiple joint sites simultaneously, where the hyperuricemia and resulting gouty arthritis stem from an identifiable underlying condition other than lead exposure, renal impairment, or drug use.
Verified May 8, 2026 · 6 sources ↓
- Status
- Billable
- Chapter
- 13
- Related CPT
- 10
- Region
- Multi-region
Documentation tips
What should appear in the chart to support M10.49.
Source · Editorial brief grounded in 6 cited references ↓
- Name each affected joint explicitly (e.g., right first MTP and left wrist) — 'multiple joints' without specificity is insufficient to justify this code over a single-site code.
- Document the underlying cause of secondary gout by diagnosis, not just the lab finding; a serum urate level alone does not establish secondary etiology.
- Record whether this is an acute flare or chronic/tophaceous presentation — chronic gout maps to M1A.49, not M10.49.
- Sequence the causative condition first per the M10.4 'Code First associated condition' instruction and note that linkage explicitly in the encounter documentation.
- Capture any associated organ manifestations (renal calculi, cardiomyopathy, glomerulonephritis) so coders can append the required additional codes at the M10 category level.
- Distinguish 'other secondary gout' from drug-induced (M10.1x), lead-induced (M10.2x), and renal-impairment gout (M10.3x) — document that none of these specific etiologies apply if coding M10.49.
Related CPT procedures
Procedure codes commonly billed with M10.49. Linking the right diagnosis to the right procedure is what establishes medical necessity.
Source · CMS LCDs · AAOS specialty guidance · claims-pattern analysis
Common coding pitfalls
The recurring mistakes coders make with M10.49 and adjacent codes.
Source · Editorial brief grounded in CDC ICD-10-CM tabular guidance, AAOS coding references, and cited references ↓
- Sequencing M10.49 first when a 'Code First' underlying condition is present — the causative systemic disease belongs in the primary position.
- Using M10.49 for chronic tophaceous gout at multiple sites — that presentation requires M1A.49, since M10 is limited to acute gout/gout flares and chronic gout is Excludes2.
- Defaulting to M10.9 (unspecified gout) when the record documents both a secondary etiology and polyarticular involvement — M10.49 is the correct billable code in that scenario.
- Conflating renal-impairment secondary gout (M10.39) with 'other' secondary gout (M10.49) — if chronic kidney disease or renal dysfunction is the documented cause, use M10.3x, not M10.4x.
- Assigning M10.49 when only one joint is affected — use the appropriate single-site M10.4x code (M10.40–M10.47) when laterality and site are documented.
Clinical context
Source · Editorial summary grounded in 6 cited references ↓
M10.49 applies when a patient presents with acute gouty arthritis affecting more than one joint region and the gout is attributable to a secondary cause — such as a hematologic disorder, enzyme deficiency, or another systemic disease — that does not fall under the drug-induced (M10.1x), lead-induced (M10.2x), or renal-impairment-related (M10.3x) subcategories. The 'multiple sites' qualifier requires documentation of polyarticular involvement; if the flare is confined to a single joint region, select the site-specific M10.4x code instead.
Critical sequencing rule: M10.4x carries a 'Code First' instruction for the associated underlying condition. The causative disorder (e.g., a hematologic malignancy, glucose-6-phosphatase deficiency, or other metabolic disease) must be sequenced before M10.49 unless the reason for the encounter is the gout itself — follow standard ICD-10-CM sequencing guidelines for that determination. Chronic gout is explicitly excluded from this category (Excludes2: M1A.-).
Because M10.49 covers acute flares, verify the encounter is not for chronic tophaceous gout, which belongs under M1A.49. Use additional codes as instructed at the M10 category level to capture any associated manifestations: autonomic neuropathy (G99.0), uric acid urolithiasis (N22), cardiomyopathy (I43), or glomerular disease (N08).
Sibling codes
Other billable codes under M10.4 (laterality / anatomic variants).
Frequently asked questions
Source · Generated from the editorial pipeline, verified against 6 cited references ↓
01What qualifies as 'multiple sites' for M10.49?
02Which secondary causes of gout belong under M10.49 versus M10.3x?
03Does M10.49 require a 'Code First' companion code?
04How do I distinguish M10.49 from M1A.49?
05Can M10.49 be used for drug-induced polyarticular gout?
06Should I add additional codes for organ manifestations when reporting M10.49?
07What CPT procedures are commonly billed with M10.49?
Sources & references
Editorial content was developed using the following public sources. Last verified May 8, 2026.
- 01CDC ICD-10-CM Tabular List 2026 (effective October 1, 2025)
- 02icd10data.comhttps://www.icd10data.com/ICD10CM/Codes/M00-M99/M05-M14/M10-/M10.49
- 03aapc.comhttps://www.aapc.com/codes/icd-10-codes/M10.49
- 04aapc.comhttps://www.aapc.com/codes/icd-10-codes/M10.4
- 05precisionhub.comhttps://precisionhub.com/types-of-gout-icd-10-codes-complete-guide-for-accurate-diagnosis/
- 06cms.govhttps://www.cms.gov/Medicare/Coding/ICD10/Downloads/2019-ICD10-Coding-Guidelines-.pdf
Mira AI Scribe
The Mira AI Scribe captures polyarticular joint involvement by name, the documented underlying systemic condition driving uric acid overproduction or underexcretion, acute flare status versus chronic tophaceous presentation, and any associated organ findings (renal stones, nephropathy). This prevents defaulting to unspecified M10.9, missing the mandatory 'Code First' sequencing instruction, and incorrect migration to M1A.49 for what is actually an acute flare.
See how Mira captures M10.49 documentation