Soft tissue repair · Wrist

25145

Sequestrectomy of the forearm and/or wrist — surgical removal of necrotic or infected bone tissue (sequestrum) from the radius, ulna, or wrist, typically performed for osteomyelitis or bone abscess.

Verified May 8, 2026 · 4 sources ↓

Medicare
$502.35
Total RVUs
15.04
Global, days
90
Region
Wrist
Drawn from CMSHhs

Documentation requirements

What must appear in the operative or office note to support the claim.

Source · Editorial brief grounded in 4 cited references ↓

  • Specify the bone(s) operated on (radius, ulna, and/or specific carpal bone)
  • Document the clinical indication — osteomyelitis, bone abscess, or other source of bone necrosis — with imaging or lab correlation
  • Describe the extent of bone excision and debridement performed, including any saucerization or craterization technique used
  • Record intraoperative cultures obtained and any concurrent soft-tissue debridement
  • Note whether fluoroscopy or other imaging guidance was used intraoperatively
  • Include pathology submission details for the excised bone specimen to support medical necessity

Applicable modifiers

Modifiers commonly billed with this code.

Source · AMA CPT modifier descriptors · CMS NCCI Policy Manual

What this code covers

Source · Editorial summary grounded in 4 cited references ↓

CPT 25145 covers open surgical removal of a bone sequestrum from the forearm (radius and/or ulna) and/or wrist. The procedure addresses dead or infected bone — most commonly resulting from osteomyelitis or a bone abscess — by excising the necrotic fragment and debriding the surrounding diseased tissue. It falls under the partial bone excision family (sequestrectomy, craterization, saucerization, diaphysectomy) and carries a 90-day global period.

The 90-day global covers the operative day, the day-before visit, and all routine post-op management through day 90. Wound checks, dressing changes, and suture removal within that window are bundled. Use modifier 24 for unrelated E&M visits and modifier 78 for an unplanned return to the OR for a related complication during the global. Effective January 1, 2024, CMS added 25145 to the list of CPT codes billable with HCPCS device code C1602 in the hospital outpatient setting when an applicable pass-through device is used — a claim-level requirement that catches HOPD billers off guard.

Document the specific bone(s) involved (radius, ulna, carpal), the extent of resection, cultures obtained, and any concurrent wound debridement. Payers scrutinize whether the level of bone involvement justifies the sequestrectomy code versus a simple debridement. Pathology submission of the excised bone fragment strengthens medical necessity and provides audit-proof documentation of the infected or necrotic tissue.

RVU & reimbursement

Component RVUs and Medicare national rate. Actual payment varies by GPCI locality.

Source · CMS Physician Fee Schedule, RVU26A · January 2026

Work RVU6.38
Practice expense RVU7.32
Malpractice RVU1.34
Total RVU15.04
Medicare national rate$502.35
Global period90 days

Payment by site of service

Medicare pays different rates by setting. HOPD typically pays substantially more than ASC for the same procedure.

Source · CMS OPPS Addendum B·ASC HCPCS payment rates·2026

SettingMedicare rate (national)
Office (PFS non-facility)
Procedure performed in physician's office
$502.35
HOPD (APC 5113)
Hospital outpatient department
$3,342.87
ASC (PI A2)
Ambulatory surgical center (freestanding)
$1,644.87

Common denial reasons

The recurring reasons claims for CPT 25145 get rejected.

Source · Editorial brief grounded in CMS NCCI edits, AAOS coding appeals, and cited references ↓

  • Medical necessity not established — missing pre-op imaging (X-ray, MRI, or bone scan) confirming osteomyelitis or bone abscess
  • Operative note describes only soft-tissue debridement without clear documentation of bone removal, triggering downcoding
  • HOPD claims missing required HCPCS device code C1602 when a qualifying pass-through device was used, per CMS CR 13488
  • Global period violations — routine post-op wound care billed separately within the 90-day global without appropriate modifier
  • Concurrent debridement or bone biopsy codes billed without modifier 59 or XS when performed at a separate anatomic site

Frequently asked questions

Source · Generated from the editorial pipeline, verified against 4 cited references ↓

01What is the global period for CPT 25145?
90 days. All routine post-op visits, wound checks, and dressing changes from the day before surgery through day 90 are bundled. Bill modifier 24 for unrelated E&M services and modifier 78 for an unplanned return to the OR for a related complication during that window.
02Can 25145 be billed with a bone biopsy code at the same encounter?
Only if the biopsy was performed at a separate anatomic site or as a distinctly separate service. If the biopsy and sequestrectomy are performed on the same bone at the same encounter, report only the more definitive procedure. Use modifier 59 or XS if separate site justification exists and document it explicitly.
03What is HCPCS C1602 and when does it apply to 25145?
C1602 is a device pass-through code for certain bone void filler devices. CMS added 25145 to the list of CPT codes that must be billed alongside C1602 in the HOPD setting effective January 1, 2024, when a qualifying device is used. Omitting C1602 from the claim when applicable will result in the device cost being excluded from pass-through payment.
04Is 25145 appropriate for debridement of osteomyelitis without formal sequestrectomy?
Only if dead or infected bone was actually removed. If the procedure involved wound irrigation and soft-tissue debridement only, without resection of cortical or cancellous bone, 25145 does not apply. The operative note must describe bone excision to support the code.
05How should bilateral forearm sequestrectomies be coded?
Report 25145 twice with modifiers LT and RT on separate line items. Do not use modifier 50 for bilateral upper extremity procedures when the sites are distinct bilateral structures — use side-specific modifiers and apply the 51 multiple procedure reduction rules.
06Can an E&M be billed on the same day as 25145?
Yes, if it is a significant and separately identifiable service unrelated to the decision to perform the sequestrectomy. Attach modifier 25 to the E&M. Document a separate, distinct reason for the evaluation in the note — a shared chief complaint will not support separate billing.

Mira AI Scribe

Mira's AI scribe captures the specific bone(s) excised (radius, ulna, carpal), the operative technique (sequestrectomy, saucerization, or craterization), the clinical indication (osteomyelitis, bone abscess), cultures obtained, and extent of debridement directly from dictation. That prevents the most common audit flag for 25145 — operative notes that document wound irrigation without clearly describing bone removal, which gives payers grounds to downcode to a soft-tissue debridement code.

See how Mira captures CPT 25145 documentation

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